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A first case of Mixta calida bacteremia and meningitis in a 5-week old child
Stijn Van Hees1,2,3, Sarah Keulemans4, Koen Vanden Driessche5
1Department of Clinical Microbiology, AZ Sint-Maarten, Mechelen, Belgium.
Insights
Mixta calida, previously considered non-pathogenic, caused bacteremia and meningitis in an infant. This case provides the first strong evidence of Mixta calida
Area of Science:
- Microbiology
- Infectious Diseases
- Clinical Medicine
Background:
- Mixta calida (formerly Pantoea calida) is an Enterobacterales bacterium.
- Historically, Mixta calida was considered non-pathogenic.
- Previous reports lacked conclusive evidence of pathogenicity due to contamination concerns.
Abstract:
Mixta calida, previously known as Pantoea calida, was initially isolated from powdered infant milk in 2010. It falls within the Erwiniaceae family (class: Enterobacterales). While Mixta calida was traditionally regarded as non-pathogenic, we now present a case of Mixta calida bacteraemia and meningitis in a 5-week-old child, successfully treated with cefotaxime. This case, in contrast to prior reports with potential contamination issues, is the first to offer compelling evidence of Mixta calida's pathogenicity in humans.
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