Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Liver Histology01:27

Liver Histology

650
The microscopic anatomy of the liver is a complex and intricate system that comprises numerous structural units known as liver lobules, each of which is comparable in size to a sesame seed. These hexagonal structures consist of plates of liver cells or hepatocytes, which are characterized by their versatility and abundance of cellular apparatus like rough and smooth ER, Golgi apparatus, peroxisomes, and mitochondria.
Hepatocytes perform a variety of essential functions. They secrete...
650
Hepatic Portal System01:21

Hepatic Portal System

1.1K
The hepatic portal system, a critical part of our circulatory framework, transports nutrient-laden, deoxygenated blood from the gastrointestinal tract and spleen to the liver. This ingenious system plays an indispensable role in maintaining our body's metabolic equilibrium.
At its core, the hepatic portal vein is the result of a confluence of the superior and inferior mesenteric veins along with the splenic vein. Each of these veins has a unique role. The superior mesenteric vein is...
1.1K
Diseases of the Liver and Gallbladder01:26

Diseases of the Liver and Gallbladder

492
Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
492
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

427
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
427
Disorders of Hemostasis01:24

Disorders of Hemostasis

758
Hemostasis, the process that stops bleeding after a blood vessel injury, is crucial for maintaining the integrity of the circulatory system. However, disorders of hemostasis can disrupt this delicate balance, leading to either excessive clotting or bleeding. These disorders can be broadly classified into thromboembolic disorders and bleeding disorders.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
758
Liver Physiology01:30

Liver Physiology

461
The liver, an essential organ in the human body, performs over 200 vital functions that can be broadly categorized into metabolic, hematological, endocrine regulation, and bile production.
Metabolic Regulation:
The liver is the central organ involved in regulating blood composition. It stabilizes blood glucose levels, maintaining them within the range of  70–110 mg/dL. When these levels drop, the liver breaks down glycogen reserves and releases glucose into the bloodstream. It can...
461

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

First-in-Human Safety and Feasibility of Nodal and Pedal MR Lymphangiography with Gadopiclenol.

Radiology. Cardiothoracic imaging·2026
Same authorSame journal

Invited Commentary: Early Detection of Pancreatic Cancer: Are We Up for the Challenge?

Radiographics : a review publication of the Radiological Society of North America, Inc·2026
Same author

Reply: Regarding "multiparametric magnetic resonance imaging, diffusion-weighted magnetic resonance imaging, and magnetic resonance elastography: differentiating benign and malignant liver lesions".

Diagnostic and interventional radiology (Ankara, Turkey)·2026
Same author

Contrast-enhanced US Evaluation of Indeterminate Focal Renal Masses.

Radiographics : a review publication of the Radiological Society of North America, Inc·2026
Same author

International Multidisciplinary Consensus Report on Definitions, Diagnostic Criteria, and Management of Fatty Pancreas: A Joint Statement Endorsed by EPC, APA, EASD, EASL, ESGAR, ESGE, ESP, ESPCG, ESPEN, ESPGHAN, IAP, JPS, KPBA, LAPSG, and UEG.

United European gastroenterology journal·2026
Same author

Learning from experience: cadaveric simulation of CT- and ultrasound-guided procedures in radiology fellowship training.

Current problems in diagnostic radiology·2026
Same journal

MRI of Lesions Growing Along the Pituitary Stalk.

Radiographics : a review publication of the Radiological Society of North America, Inc·2026
Same journal

Radiology Board Examinations: A Fundamental Shift.

Radiographics : a review publication of the Radiological Society of North America, Inc·2026
Same journal

Early Pancreatic Cancer: Clinical Implications, Workup, and Imaging Findings with Histopathologic Correlation for Personalized Surveillance.

Radiographics : a review publication of the Radiological Society of North America, Inc·2026
Same journal

Comprehensive Approach to Prostate Cancer Metastasis Mimics at Prostate-Specific Membrane Antigen PET/CT.

Radiographics : a review publication of the Radiological Society of North America, Inc·2026
Same journal

Invited Commentary: Postdeployment Monitoring of AI in Radiology: Beyond the Test Set.

Radiographics : a review publication of the Radiological Society of North America, Inc·2026
See all related articles

Related Experiment Video

Updated: Jun 16, 2025

A Standardized Method for the Analysis of Liver Sinusoidal Endothelial Cells and Their Fenestrations by Scanning Electron Microscopy
08:38

A Standardized Method for the Analysis of Liver Sinusoidal Endothelial Cells and Their Fenestrations by Scanning Electron Microscopy

Published on: April 30, 2015

14.4K

Hepatic Sinusoidal Disorders.

Sudhakar K Venkatesh1, Kelly C Harper1, Amir A Borhani1

  • 1From the Department of Radiology, Abdominal Imaging Division, Mayo Clinic, 200 First St SW, Rochester, MN 55905 (S.K.V., K.C.H., S.M.T., S.H., P.J.N., C.N.G., C.L.W.); Department of Medical Imaging, University of Ottawa, Ottawa, Ontario, Canada (K.C.H.); Department of Abdominal Imaging, Northwestern Memorial Hospital, Chicago, Ill (A.A.B.); Department of Abdominal Imaging, University of Pittsburgh, Pittsburgh, Pa (A.F., F.H.M.); Department of Anatomic Pathology, Mayo Clinic, Rochester, Minn (E.Z.M.C., M.S.T.); and Department of Radiology, Hacettepe University, Ankara, Turkey (I.S.I.).

Radiographics : a Review Publication of the Radiological Society of North America, Inc
|August 15, 2024
PubMed
Summary
This summary is machine-generated.

Imaging plays a crucial role in diagnosing liver sinusoidal disorders, such as sinusoidal obstruction syndrome (SOS). Understanding specific imaging features aids early detection and differentiation of these conditions.

More Related Videos

Isolation and Characterization of Mouse Primary Liver Sinusoidal Endothelial Cells
08:22

Isolation and Characterization of Mouse Primary Liver Sinusoidal Endothelial Cells

Published on: December 16, 2021

6.5K
In vivo Liver Endocytosis Followed by Purification of Liver Cells by Liver Perfusion
12:35

In vivo Liver Endocytosis Followed by Purification of Liver Cells by Liver Perfusion

Published on: November 10, 2011

19.0K

Related Experiment Videos

Last Updated: Jun 16, 2025

A Standardized Method for the Analysis of Liver Sinusoidal Endothelial Cells and Their Fenestrations by Scanning Electron Microscopy
08:38

A Standardized Method for the Analysis of Liver Sinusoidal Endothelial Cells and Their Fenestrations by Scanning Electron Microscopy

Published on: April 30, 2015

14.4K
Isolation and Characterization of Mouse Primary Liver Sinusoidal Endothelial Cells
08:22

Isolation and Characterization of Mouse Primary Liver Sinusoidal Endothelial Cells

Published on: December 16, 2021

6.5K
In vivo Liver Endocytosis Followed by Purification of Liver Cells by Liver Perfusion
12:35

In vivo Liver Endocytosis Followed by Purification of Liver Cells by Liver Perfusion

Published on: November 10, 2011

19.0K

Area of Science:

  • Radiology
  • Hepatology
  • Vascular Biology

Background:

  • Hepatic sinusoids are vital microcirculatory structures in the liver.
  • Disorders like sinusoidal obstruction syndrome (SOS) and neoplasms can be life-threatening.
  • Clinical symptoms are often nonspecific, necessitating advanced diagnostics.

Purpose of the Study:

  • To review the pathogenesis, clinical features, and imaging findings of hepatic sinusoidal disorders.
  • To emphasize the role of imaging in early diagnosis and identifying the cause of these conditions.
  • To highlight specific imaging patterns suggestive of different sinusoidal pathologies.

Main Methods:

  • Review of literature on hepatic sinusoidal disorders and their imaging manifestations.
  • Correlation of clinical presentations with imaging findings.
  • Emphasis on characteristic imaging features for conditions like SOS and neoplasms.

Main Results:

  • Hepatic sinusoidal disorders encompass a range of conditions including sinusoidal dilatation, SOS, cellular infiltration, and neoplasms.
  • Nonspecific clinical signs like pain, jaundice, and hepatomegaly can mask serious underlying pathology.
  • Distinct imaging patterns, such as mosaic enhancement for sinusoidal dilatation and peripheral hypointensity for SOS, aid diagnosis.

Conclusions:

  • A thorough understanding of imaging manifestations is key for early diagnosis of hepatic sinusoidal disorders.
  • Specific imaging features can guide the workup and differentiate between various causes.
  • Radiologists play a critical role in detecting subclinical disease and identifying specific sinusoidal pathologies.