Related Experiment Video

Updated: Jun 16, 2025

Vaccinia Virus Infection & Temporal Analysis of Virus Gene Expression: Part 1
12:00

Vaccinia Virus Infection & Temporal Analysis of Virus Gene Expression: Part 1

Published on: April 8, 2009

10.3K

What the pox? Review of poxviruses affecting humans

D Jane Hata1, Eleanor A Powell2, Meghan W Starolis3

  • 1Department of Pathology and Laboratory Medicine, Mayo Clinic Florida, 4500 San Pablo Rd., Jacksonville, FL 32224 USA.

Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology
|August 15, 2024
PubMed

Insights

Human mpox outbreaks and borealpox highlight the Poxviridae family

Area of Science:

  • Virology
  • Zoonotic Diseases
  • Public Health

Background:

  • Recent mpox outbreaks and borealpox underscore the zoonotic potential of Poxviridae.
  • Poxviruses pose a significant public health concern due to their diverse hosts and transmission routes.

Purpose of the Study:

  • To review human-affecting poxviruses, including less common Poxviridae members.
  • To discuss the pathogenesis, epidemiology, and diagnostics of these viruses.

Main Methods:

  • Literature review of poxviruses affecting humans.
  • Examination of pathogenesis, epidemiology, and diagnostic approaches.

Main Results:

  • Comprehensive overview of human poxviruses, detailing pathogenesis and epidemiology.
  • Highlights less commonly encountered Poxviridae and their diagnostic methods.

Conclusions:

  • Poxviridae represent a significant zoonotic threat requiring continued surveillance.
  • Understanding poxvirus pathogenesis, epidemiology, and diagnostics is crucial for public health preparedness.
Keywords:
MpoxOrthopoxvirusPoxvirusZoonotic poxviruses

More Related Videos

Vaccinia Reporter Viruses for Quantifying Viral Function at All Stages of Gene Expression10:48

Vaccinia Reporter Viruses for Quantifying Viral Function at All Stages of Gene Expression

Published on: May 15, 2014

11.4K
Vaccinia Virus Infection & Temporal Analysis of Virus Gene Expression: Part 307:35

Vaccinia Virus Infection & Temporal Analysis of Virus Gene Expression: Part 3

Published on: April 13, 2009

8.1K

Related Concept Videos

Viral Recombination00:57

Viral Recombination

Cells are sometimes infected by more than one virus at once. When two viruses disassemble to expose their genomes for replication in the same cell, similar regions of their genomes can pair together and exchange sequences in a process called recombination. Alternatively, viruses with segmented genomes can swap segments in a process called reassortment.
23.3K
Retroviruses02:33

Retroviruses

Retroviruses and retrotransposons both insert copies of their genetic elements into the genome of the host cell. Thus, the viral genes are passed on when the host genome is replicated or translated. A typical retroviral DNA sequence contains 3-4 genes that encode the different proteins required for its structural assembly and function as a molecular parasite. This DNA is transcribed into a single mRNA, which is very similar in structure to conventional mRNAs, i.e., it is capped at the 5’...
12.2K
Retrovirus Life Cycles01:10

Retrovirus Life Cycles

Retroviruses have a single-stranded RNA genome that undergoes a special form of replication. Once the retrovirus has entered the host cell, an enzyme called reverse transcriptase synthesizes double-stranded DNA from the retroviral RNA genome. This DNA copy of the genome is then integrated into the host’s genome inside the nucleus via an enzyme called integrase. Consequently, the retroviral genome is transcribed into RNA whenever the host’s genome is transcribed, allowing the...
45.8K