Related Experiment Video
Updated: Jun 16, 2025

Adapting Human Videofluoroscopic Swallow Study Methods to Detect and Characterize Dysphagia in Murine Disease Models
Published on: March 1, 2015
[Fiber endoscopic evaluation of swallowing (FEES) - an important tool for diagnosing myasthenia gravis]
Michael Kowar1, Monika Frackowiak1, Christiane Kaufhold1
1Klinik für Geriatrie mit Neurologie und Tagesklinik, Johanniter gGmbH, Johanniter-Krankenhaus Bonn.
History And Admission Findings:
A 76-year old man was admitted with a globus sensation and weight loss for further investigations to our geriatric ward. A gastroscopic evaluation executed before had been unremarkable.
Investigations:
Physical examination was unremarkable, including a neurological examination.
Treatment And Course:
All radiological findings (computer tomography of chest, abdomen and neck) were unremarkable. In a FEES investigation we found retentions and a reduction of frequency of swallowing after a while. During the investigation the patient complained about a muscular weakness in his neck. The assumed diagnosis of a myasthenia gravis was confirmed by antibodies against acetylcholine receptors and a decrement in repetitive irritation of the orbicularis and trapezius muscle.
Conclusion:
FEES can be a valid diagnosis tool for a pharyngeal type of a myasthenia gravis.
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