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Corrigendum: Paclitaxel-incorporated nanoparticles improve functional recovery after spinal cord injury

Xinzhu Zhang1,2, Wu Xiong1,3, Guang Kong1,4,5

  • 1Nanjing Medical University, Nanjing, China.

Frontiers in Pharmacology
|August 16, 2024
PubMed

Keywords:
chondroitin sulfate proteoglycan inhibitionpaclitaxelspermine-functionalized acetalated dextranspinal cord injury

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Spinal cord injury progresses through two interconnected phases: primary injury and secondary injury.Primary InjuryPrimary injury happens at the moment of trauma and involves immediate mechanical damage to the spinal cord.Compression happens when broken vertebrae, herniated discs, or accumulating blood (such as a hematoma) press directly against the spinal cord, distorting its normal shape and function. In cases of contusion, the cord is bruised by a blunt force (like penetrating injuries or...
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