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Updated: May 1, 2026
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Reliable Mechanochemistry: Protocols for Reproducible Outcomes of Neat and Liquid Assisted Ball-mill Grinding Experiments
Published on: January 23, 2018
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Linking mechanochemistry with the green chemistry principles: Review article
Sergi Arfelis1,2,3, Ana I Martín-Perales2,4, Remy Nguyen5
1UNESCO Chair in Life Cycle and Climate Change ESCI-UPF, Pg. Pujades 1, 08003, Barcelona, Spain.
Heliyon
|August 16, 2024
Summary
Flow mechanochemistry, including single-screw extrusion (SSE) and twin-screw extrusion (TSE), offers greener alternatives for industrial production. These methods advance synthesis and material fabrication, aligning with green chemistry principles.
Area of Science:
- Green Chemistry
- Materials Science
- Chemical Engineering
Background:
- Traditional batch mechanochemistry faces limitations in industrial production.
- Integrating flow processes with mechanochemistry presents innovative solutions.
- Emerging technologies like SSE, TSE, and ICHeM are transforming chemical synthesis and material fabrication.
Purpose of the Study:
- To compile and analyze cutting-edge research in mechanochemistry for green chemistry applications.
- To highlight the advantages of flow mechanochemistry over traditional methods.
- To review recent advancements in SSE, TSE, and ICHeM technologies.
Main Methods:
- Literature review focusing on articles published between 2020-2022.
- Screening methodology to select 60 relevant articles.
- Analysis of product types, reactants, milling ball sizes, and reaction conditions.
Main Results:
- Flow mechanochemistry, including SSE and TSE, offers significant advantages over conventional solvothermal processes.
- Ball milling techniques require less solvent and enhance reaction rates and conversion.
- These methods are applicable to polymer production, API synthesis, nanomaterial fabrication, and biomass valorization.
Conclusions:
- Flow mechanochemistry represents a greener and more efficient approach for diverse industrial applications.
- Continued research in mechanochemistry is vital for sustainable chemical production.
- SSE, TSE, and ICHeM are key technologies driving innovation in green chemistry.
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