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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
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Related Experiment Video

Updated: Jun 16, 2025

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors
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Plexiform's perplexities: a tale of two plexiform neurofibromas.

Aditya Sriharsha Pedaprolu1, Rajesh Gattani1, Suhas Jajoo1

  • 1Department of General Surgery, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Sawangi, Wardha, Maharashtra 442001, India.

Journal of Surgical Case Reports
|August 16, 2024
PubMed
Summary

Plexiform neurofibroma (PF), a rare neurofibromatosis type 1 variant, presents with characteristic skin changes. This study highlights typical and atypical cases, emphasizing surgery and follow-up for management.

Area of Science:

  • Dermatology
  • Oncology
  • Genetics

Background:

  • Plexiform neurofibroma (PF) is a rare, benign tumor arising from peripheral nerve sheaths, often associated with neurofibromatosis type 1.
Keywords:
café-au-lait maculesnerve tumorneurofibromaneurofibromatosisplexiform neurofibromavon Recklinghausen’s disease

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  • These tumors can cause significant disfigurement and involve surrounding connective and dermal tissues.
  • Diagnosis is typically aided by characteristic cutaneous changes.