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Updated: Jun 16, 2025

A Micropatterning Assay for Measuring Cell Chirality
Published on: March 11, 2022
Active chiral flows in the separating wall during cell division
Vijit Ganguly1, Mainak Chatterjee1, Anirban Sain1
1Physics Department, Indian Institute of Technology-Bombay, Powai, Mumbai 400076, India.
Abstract:
Material flow in the actomyosin cortex of a cell, during cell division, has been found to be chiral in nature. It has been attributed to active chiral torques generated in the actomyosin cortex. Here, we explore the possible signature of such chirality during the growth of the intra-cellular membrane partition, which physically divides the cell into two compartments. We use standard hydrodynamic theory of active gel to predict possible chiral flow structures in the growing partition. While the flows in the growing annular-shaped membrane partition is believed to be radial, it can also develop non-zero azimuthal velocity components (rotation) due to chirality. We show that the direction of rotation (clock or anti-clockwise) will not solely be decided by the sign of the active chiral torque but also by the relative strengths of rotational viscosity and flow coupling parameter.
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