Jove
Visualize
Contact Us

Related Concept Videos

Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy01:26

Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy

63
This lesson explores three gastrointestinal imaging techniques: radionuclide testing, colonic transit studies, and virtual colonoscopy.
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and...
63
Endoscopic Procedures II: Colonoscopy01:25

Endoscopic Procedures II: Colonoscopy

66
The colon, or large intestine, is the final segment of the digestive system. Its primary functions include absorbing water and vitamins produced by gut bacteria and transforming waste from liquid to solid to form stool. In adults, the large intestine is approximately 5 feet long and consists of four main sections:
66
Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

134
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
134
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies
  1. Home
  3. Indocyanine Green Near-infrared Fluorescence Bowel Perfusion Assessment To Prevent Anastomotic Leakage In Minimally Invasive Colorectal Surgery (avoid): A Multicentre, Randomised, Controlled, Phase 3 Trial.
  1. Home
  3. Indocyanine Green Near-infrared Fluorescence Bowel Perfusion Assessment To Prevent Anastomotic Leakage In Minimally Invasive Colorectal Surgery (avoid): A Multicentre, Randomised, Controlled, Phase 3 Trial.

Related Experiment Video

The Role of Indocyanine Green Fluorescence in Complex Laparoscopic Cholecystectomy Navigation
03:27

The Role of Indocyanine Green Fluorescence in Complex Laparoscopic Cholecystectomy Navigation

Published on: January 31, 2025

403

Indocyanine green near-infrared fluorescence bowel perfusion assessment to prevent anastomotic leakage in minimally

Robin A Faber1, Ruben P J Meijer1, Daphne H M Droogh1

  • 1Department of Surgery, Leiden University Medical Center, Leiden, Netherlands.

The Lancet. Gastroenterology & Hepatology
|August 16, 2024

View abstract on PubMed

Summary
This summary is machine-generated.

More Related Videos

Indocyanine Green-Guided Intraoperative Imaging to Facilitate Video-Assisted Retroperitoneal Debridement for Treating Acute Necrotizing Pancreatitis
04:01

Indocyanine Green-Guided Intraoperative Imaging to Facilitate Video-Assisted Retroperitoneal Debridement for Treating Acute Necrotizing Pancreatitis

Published on: September 8, 2022

2.4K
Fluorescent Laparoscopic Central Hepatectomy for Liver Cancer Using Indocyanine Green Negative Staining
03:23

Fluorescent Laparoscopic Central Hepatectomy for Liver Cancer Using Indocyanine Green Negative Staining

Published on: March 17, 2023

710

Related Experiment Videos

The Role of Indocyanine Green Fluorescence in Complex Laparoscopic Cholecystectomy Navigation
03:27

The Role of Indocyanine Green Fluorescence in Complex Laparoscopic Cholecystectomy Navigation

Published on: January 31, 2025

403
Indocyanine Green-Guided Intraoperative Imaging to Facilitate Video-Assisted Retroperitoneal Debridement for Treating Acute Necrotizing Pancreatitis
04:01

Indocyanine Green-Guided Intraoperative Imaging to Facilitate Video-Assisted Retroperitoneal Debridement for Treating Acute Necrotizing Pancreatitis

Published on: September 8, 2022

2.4K
Fluorescent Laparoscopic Central Hepatectomy for Liver Cancer Using Indocyanine Green Negative Staining
03:23

Fluorescent Laparoscopic Central Hepatectomy for Liver Cancer Using Indocyanine Green Negative Staining

Published on: March 17, 2023

710

Near-infrared (NIR) fluorescence imaging with indocyanine green (ICG) did not significantly reduce anastomotic leakage in colorectal surgery. Further studies are needed for specific patient subgroups, like rectosigmoid resections.

Area of Science:

  • Surgical Innovation
  • Medical Imaging
  • Colorectal Surgery

Background:

  • Anastomotic leakage is a severe complication in colorectal surgery, often linked to compromised bowel perfusion.
  • Conventional methods for assessing bowel perfusion have limited predictive value for anastomotic leakage.
  • Near-infrared (NIR) fluorescence imaging with indocyanine green (ICG) offers real-time assessment of bowel perfusion.

Purpose of the Study:

  • To evaluate the efficacy of fluorescence-guided bowel anastomosis (FGBA) using ICG NIR imaging in preventing anastomotic leakage.
  • To compare the rate of clinically relevant anastomotic leakage between FGBA and conventional bowel anastomosis (CBA) groups.
  • To assess the safety of ICG use in colorectal surgery.

Main Methods:

  • A multicentre, randomized, controlled, phase 3 trial involving 931 patients undergoing laparoscopic or robotic colorectal surgery.
  • Patients were assigned to either FGBA (using ICG NIR imaging) or CBA.
  • The primary outcome was the rate of clinically relevant anastomotic leakage within 90 days post-surgery.

    • Main Results:

    • The overall 90-day rate of clinically relevant anastomotic leakage was not significantly different between the FGBA (7%) and CBA (9%) groups (RR 0.77; 95% CI 0.50-1.20; p=0.24).
    • No adverse events related to ICG use were observed.
    • Serious adverse events and 90-day mortality rates were similar between the groups.

    Conclusions:

    • ICG NIR fluorescence imaging did not reduce 90-day anastomotic leakage rates across all colorectal surgeries in this trial.
    • Further research is warranted in specific subgroups, such as rectosigmoid resections, where ICG NIR may show benefit.