Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Bone marrow transplantation.

R P Gale

    Critical Reviews in Oncology/Hematology
    |January 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Bone marrow transplantation is a vital treatment for various diseases, including leukemia and genetic disorders. Ongoing research addresses challenges like graft-versus-host disease and donor availability to expand its therapeutic potential.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Impact of donor type on outcome of bone marrow transplantation for Wiskott-Aldrich syndrome: collaborative study of the International Bone Marrow Transplant Registry and the National Marrow Donor Program.

    Blood·2001
    Same author

    Effect of postremission chemotherapy before human leukocyte antigen-identical sibling transplantation for acute myelogenous leukemia in first complete remission.

    Blood·2000
    Same author

    Decreased chronic lymphocytic leukemia incidence in Asians in Los Angeles County.

    Leukemia research·2000
    Same author

    Blood stem cells compared with bone marrow as a source of hematopoietic cells for allogeneic transplantation. IBMTR Histocompatibility and Stem Cell Sources Working Committee and the European Group for Blood and Marrow Transplantation (EBMT).

    Blood·2000
    Same author

    T-cell depletion of bone marrow transplants for leukemia from donors other than HLA-identical siblings: advantage of T-cell antibodies with narrow specificities.

    Blood·2000
    Same author

    Effect of nucleated marrow cell dose on relapse and survival in identical twin bone marrow transplants for leukemia.

    Blood·2000
    Same journal

    Opportunities and Challenges of Dihydrodiol dehydrogenase Expression in Hepatocellular carcinoma.

    Critical reviews in oncology/hematology·2026
    Same journal

    Ferroptosis in Glioblastoma: Molecular Determinants, Immune Crosstalk, and Therapeutic Opportunities.

    Critical reviews in oncology/hematology·2026
    Same journal

    Beyond Oncogenesis: The emerging role of EZH2 in Tumor Microenvironment.

    Critical reviews in oncology/hematology·2026
    Same journal

    Cross-Scale Bioanalytical Integration for Decoding Tumour Regulatory Plasticity in Oncology.

    Critical reviews in oncology/hematology·2026
    Same journal

    Organoids in Biliary Tract Cancers: Advances in Modeling Strategies and Translational Applications.

    Critical reviews in oncology/hematology·2026
    Same journal

    Corrigendum to "Management of atypical cartilaginous tumors (ACT): An Italian Sarcoma Group (ISG) consensus document" [Crit. Rev. Oncol. Hematol. 223 (2026) 105358].

    Critical reviews in oncology/hematology·2026
    See all related articles

    Area of Science:

    • Hematology
    • Immunology
    • Genetics
    • Oncology

    Background:

    • Bone marrow transplantation (BMT) is a well-established therapy for aplastic anemia and leukemia.
    • Its application in treating solid tumors, immune deficiencies, and genetic disorders is expanding.
    • Controversy exists regarding BMT's role in certain conditions, such as leukemia in remission.

    Purpose of the Study:

    • To review the established and controversial applications of bone marrow transplantation.
    • To highlight the successes in treating genetic disorders like severe combined immunodeficiency and thalassemia.
    • To discuss current challenges and future research directions in BMT.

    Main Methods:

    • Review of current literature on bone marrow transplantation.

    Related Experiment Videos

  • Analysis of established indications and emerging applications.
  • Discussion of unresolved issues and future research avenues.

    • Main Results:

    • BMT is effective for aplastic anemia, leukemia, and numerous genetic disorders.
    • Significant challenges remain, including graft-versus-host disease, interstitial pneumonia, and donor scarcity.
    • Potential future applications include use with solid-organ grafts and gene therapy.

    Conclusions:

    • Bone marrow transplantation offers curative potential for a wide range of diseases.
    • Addressing complications and donor availability are critical for broader BMT application.
    • Future research aims to expand BMT indications and integrate it with other advanced therapies.