Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Amyloid P component in normal human placentae.

A M Khan, F Walker

    Placenta
    |November 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Amyloid P component, a key protein, was found in human placentas starting at 16 weeks gestation. Its presence increases with gestational age, suggesting a role in placental maturation.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Intensified pulmonary tuberculosis case finding among selected high-risk clinical groups attending secondary level public health care facilities in Bhubaneswar.

    Indian journal of medical microbiology·2026
    Same author

    Computational solutions for fractional-order modeling of Visceral Leishmaniasis using Caputo derivatives.

    Scientific reports·2026
    Same author

    Long-Range Transverse-Momentum Correlations and Radial Flow in Pb-Pb Collisions at the LHC.

    Physical review letters·2026
    Same author

    Search for Quasiparticle Scattering in the Quark-Gluon Plasma with Jet Splittings in pp and Pb-Pb Collisions at sqrt[s_{NN}]=5.02  TeV.

    Physical review letters·2025
    Same author

    First Measurement of A=4 Hypernuclei and Antihypernuclei at the LHC.

    Physical review letters·2025
    Same author

    Probing Strangeness Hadronization with Event-by-Event Production of Multistrange Hadrons.

    Physical review letters·2025
    Same journal

    Eucalyptol (1,8-cineole) relaxes umbilical veins in normoglycemic parturients and parturients with gestational diabetes mellitus by modulating ion channels: An ex vivo study.

    Placenta·2026
    Same journal

    Transcriptomic profiling of human placental explants exposed to Plasmodium falciparum reveals activation of tissue-remodeling pathways and signatures associated with the Placenta-Brain Axis.

    Placenta·2026
    Same journal

    Esomeprazole treatment targeting sFLT-1 signaling in preeclampsia improves placental and fetal outcome in mice.

    Placenta·2026
    Same journal

    α7 nicotinic acetylcholine receptor regulates decidual macrophage polarization through TLR4/NF-κB/HIF-1α-mediated glycolytic reprogramming in preeclampsia.

    Placenta·2026
    Same journal

    Progesterone-KISS1 axis impairs amniotic epithelial cell function and promotes premature rupture of membranes.

    Placenta·2026
    Same journal

    Placental iron-driven oxidative imbalance and changes in iron homeostasis in diabetes-in-pregnancy: A cross-sectional analytical study.

    Placenta·2026
    See all related articles

    Area of Science:

    • Obstetrics and Gynecology
    • Immunohistochemistry
    • Developmental Biology

    Background:

    • The human placenta undergoes significant development and maturation throughout gestation.
    • The extracellular matrix of the placenta contains various structural proteins.
    • The role of specific proteins like Amyloid P component in placental development is not fully understood.

    Purpose of the Study:

    • To investigate the presence and distribution of Amyloid P component in normal human placentae and umbilical cords.
    • To determine the temporal appearance and changes in Amyloid P component levels during gestation.
    • To explore the potential relationship between Amyloid P component and placental maturation.

    Main Methods:

    • Direct immunofluorescence technique was employed.

    Related Experiment Videos

  • Frozen sections of normal human placentae and umbilical cords were analyzed.
  • Samples were collected from various gestational durations.

    • Main Results:

    • Amyloid P component was detected from the 16th week of gestation onwards.
    • The amount of Amyloid P component progressively increased with advancing gestation.
    • Amyloid P component was localized in the perifetal capillary zone.
    • Co-localization with basement membrane-like material and reticulin fibers was observed.

    Conclusions:

    • Amyloid P component is a constituent of the developing human placenta.
    • Its increasing presence suggests a role in placental maturation.
    • Further research is warranted to elucidate the specific functions of Amyloid P component in placental development.