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Updated: Jun 16, 2025

A Method for 3D Reconstruction and Virtual Reality Analysis of Glial and Neuronal Cells
Published on: September 28, 2019
RRmorph-a new R package to map phenotypic evolutionary rates and patterns on 3D meshes
Marina Melchionna1, Silvia Castiglione2, Giorgia Girardi2
1DiSTAR, University of Naples Federico II, Naples, Italy. marina.melchionna@unina.it.
Abstract:
The study of evolutionary rates and patterns is the key to understand how natural selection shaped the current and past diversity of phenotypes. Phylogenetic comparative methods offer an array of solutions to undertake this challenging task, and help understanding phenotypic variation in full in most circumstances. However, complex, three-dimensional structures such as the skull and the brain serve disparate goals, and different portions of these phenotypes often fulfil different functions, making it hard to understand which parts truly were recruited by natural selection. In the recent past, we developed tools apt to chart evolutionary rate and patterns directly on three-dimensional shapes, according to their magnitude and direction. Here, we present further developments of these tools, which now allow to restitute the mapping of rates and patterns with full biological realism. The tools are condensed in a new R software package.
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