Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 16, 2025

In vivo Optogenetic Stimulation of the Rodent Central Nervous System
09:37

In vivo Optogenetic Stimulation of the Rodent Central Nervous System

Published on: January 15, 2015

59.3K

Optogenetics in oral and craniofacial research.

Qinmeng Zhang1,2, Luyao Song2, Mengdie Fu1,2

  • 1Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou 310000, China.

Journal of Zhejiang University. Science. B
|August 19, 2024
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Nitrate pollution sources and associated biogeochemical mechanisms in coastal groundwater affected by seawater intrusion using multiple isotopes and source apportionment models.

Marine pollution bulletin·2026
Same author

Development and Psychometric Evaluation of a Pulmonary Rehabilitation Information Needs Scale for Patients with Chronic Obstructive Pulmonary Disease.

International journal of chronic obstructive pulmonary disease·2026
Same author

Oral microbiota associated with tooth loss and cognitive function in older adults: Evidence from NHANES.

Journal of periodontology·2026
Same author

Association between oral microbial diversity and periodontitis in a nationally representative U.S. population: A cross-sectional study.

Journal of periodontology·2026
Same author

Establishment and preliminary application of an ELISA method for detecting antibodies to field strains of bovine infectious rhinotracheitis virus.

Veterinary journal (London, England : 1997)·2026
Same author

Long-Term Stability of Bone Graft After Implant Failure in Lateral Sinus Floor Elevation: A Retrospective Paired Study.

Clinical implant dentistry and related research·2026

Optogenetics, using light to control genetically modified cells, offers precise spatiotemporal control for studying oral functions and neural mechanisms. This review highlights its applications in oral research, from basic science to therapeutic potential.

Area of Science:

  • Optogenetics
  • Oral and craniofacial research

Background:

  • Optogenetics utilizes genetically engineered photosensory proteins activated by light for precise biological control.
  • It offers noninvasive, efficient spatiotemporal modulation of gene expression and cellular functions.

Purpose of the Study:

  • To review the origins and recent advancements of optogenetics in oral and craniofacial research.
  • To highlight its application in understanding neural mechanisms and oral behaviors.
  • To discuss its role in preclinical and translational studies.

Main Methods:

  • Introduction to optogenetic principles and tools (e.g., channelrhodopsin, halorhodopsin).
  • Review of optogenetic applications in studying orofacial movement, feeding behaviors, and neural circuits.
  • Analysis of optogenetics in preclinical models of trigeminal neuralgia and maxillofacial cellulitis.
Keywords:
Bacterial virulenceBehavioral scienceCell differentiationLasersNervous systemNeurophysiology

More Related Videos

Electroporation of Craniofacial Mesenchyme
07:23

Electroporation of Craniofacial Mesenchyme

Published on: November 28, 2011

11.9K
Laser-scanning Photostimulation of Optogenetically Targeted Forebrain Circuits
07:43

Laser-scanning Photostimulation of Optogenetically Targeted Forebrain Circuits

Published on: December 27, 2013

9.2K

Related Experiment Videos

Last Updated: Jun 16, 2025

In vivo Optogenetic Stimulation of the Rodent Central Nervous System
09:37

In vivo Optogenetic Stimulation of the Rodent Central Nervous System

Published on: January 15, 2015

59.3K
Electroporation of Craniofacial Mesenchyme
07:23

Electroporation of Craniofacial Mesenchyme

Published on: November 28, 2011

11.9K
Laser-scanning Photostimulation of Optogenetically Targeted Forebrain Circuits
07:43

Laser-scanning Photostimulation of Optogenetically Targeted Forebrain Circuits

Published on: December 27, 2013

9.2K
  • Examination of optogenetic control of dental pulp stem cell differentiation.

    • Main Results:

    • Optogenetics provides novel insights into basic neural mechanisms and oral behaviors.
    • Demonstrated efficacy in preclinical studies for conditions like trigeminal neuralgia.
    • Successful application in controlling stem cell differentiation for translational research.

    Conclusions:

    • Optogenetics is a powerful tool for advancing oral and craniofacial research.
    • Future directions include therapeutic applications for taste disorders, biofilm studies, tissue regeneration, and understanding oral diseases.
    • Further large animal and clinical studies are needed in dental research.