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Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease Complicated by Pachymeningitis: A Case Report

Sanjay M Khaladkar1, Prajakta P KirdatPatil1, Aryaman Dhande1

  • 1Radiodiagnosis, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth, Pune, IND.

Cureus
|August 19, 2024
PubMed

Insights

Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) can cause rare complications like pachymeningitis, affecting the dura mater. This case highlights diagnostic challenges in MOGAD with unusual presentations.

Area of Science:

  • Neurology
  • Immunology
  • Neuroinflammation

Background:

  • Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is a rare autoimmune condition targeting the central nervous system (CNS).
  • Pachymeningitis, inflammation of the dura mater, is an uncommon complication in neurological disorders.

Observation:

  • A patient presented with symptoms including vertigo, nausea, and vomiting.
  • The clinical presentation suggested a complex neurological condition.

Findings:

  • Diagnostic workup confirmed MOGAD complicated by pachymeningitis.
  • This indicates MOGAD can manifest with rare dural inflammation.

Implications:

  • This case broadens the understanding of MOGAD's diverse clinical spectrum.
  • It emphasizes the need for considering rare complications in MOGAD diagnosis and management.
Keywords:
demyelinationdural enhancementmog (myelin oligodendrocyte glycoprotein)mogad(myelin oligodendrocyte glycoprotein antibody associated disease)pachymeningitis

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