Related Experiment Video
Updated: Jun 16, 2025

Nephrotoxin Microinjection in Zebrafish to Model Acute Kidney Injury
Published on: July 17, 2016
Association of Acute Kidney Injury with Ammonia Poisoning: A Case Report
Vishal Pooniya1, Abhilash Chandra1, Namrata Rao S1
1Department of Nephrology, Dr. Ram Manohar Lohia Institute of Medical Sciences, Gomti Nagar, Lucknow, Uttar Pradesh, India.
Abstract:
Ammonia may cause poisoning due to inhalation or ingestion. Renal involvement in ammonia poisoning has been reported only once. A 30-year-old male working in an ice factory was accidentally exposed to liquid ammonia from a leaking hose, following which he had burns over his face and neck and severe abdominal pain. On day 2, he had deranged renal function, which was progressive. He was referred to us due to persistent renal dysfunction. A kidney biopsy was performed due to slow recovery of renal failure, which was suggestive of acute tubular necrosis. He was managed conservatively and showed gradual improvement over 12 days of his hospital stay. Renal functions normalized after 14 days of discharge. This case highlights the occurrence of renal involvement in ammonia poisoning.
More Related Videos
Related Concept Videos
Physical Properties of Amines
Nephrons
Acute Pancreatitis II: Clinical Manifestations and Management
Dialysis
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
2° Amines to N-Nitrosamines: Reaction with NaNO2
Basicity of Aliphatic Amines
To measure the basicity of amines, two conventions are generally used. The first defines Kb as the basicity constant for the deprotonation reaction of water by the amine, as presented in Figure 1. Conventionally, lower Kb indicates...

