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Updated: Sep 1, 2026

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The mucolipidosis III-causing mutation in GNPTAB, c.1760G>C, disrupts the development of somites in rats

Tianying Nong1, Jiangui Li2, Xia Li1

  • 1Guangzhou Institute of Pediatrics, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangdong Provincial Clinical Research Center for Child Health, Guangzhou, Guangdong 510623, China.

Genes & Diseases
|August 19, 2024
PubMed
Abstract

No abstract available in PubMed .

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The Ras Gene02:38

The Ras Gene

The Ras-gene-encoded proteins are regulators of signaling pathways controlling cell proliferation, differentiation, or cell survival. The Ras-gene family in humans constitutes three primary members—the HRas, NRas, and KRas. These genes code for four functionally distinct yet closely related proteins—the HRas, NRas, KRas4A, and KRas4B. The involvement of mutant Ras genes in human cancer was first discovered in 1982 and is among the most common causes of human tumorigenesis.
Ras is a superfamily...