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Updated: Jun 16, 2025

A Familial Hypercholesterolemia Human Liver Chimeric Mouse Model Using Induced Pluripotent Stem Cell-derived Hepatocytes
Published on: September 15, 2018
Acute Coronary Syndrome in a 9-Year-Old Girl With Homozygous Familial Hypercholesterolemia
Mishita Goel1, Snigdha Bhatia2, Christina Arand3
1Department of Cardiology, Detroit Medical Center/Wayne State University, Detroit, Michigan, USA.
Abstract:
Familial hypercholesterolemia (FH) is a prevalent and underrecognized disorder. A young girl with previously undiagnosed homozygous FH presented with acute coronary syndrome. Severe coronary ostial stenosis and severe supravalvular aortic stenosis from atheromatous plaque was discovered. This case highlights the importance of screening and timely diagnosis of FH.
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