Anomalous Coronary Artery Identified Post Heart Transplantation
Emily O'Neill1, Spencer Carter2, Alison Brann2
1Department of Medicine, University of Utah, Salt Lake City, Utah, USA.
JACC. Case Reports
|August 19, 2024
Insights
A heart transplant recipient was found to have an unusual coronary artery anomaly in the donor heart. This anomalous left circumflex artery originated from the right coronary artery, a rare finding post-transplant.
Area of Science:
- Cardiology
- Transplant Surgery
- Cardiac Imaging
Background:
- Cardiac amyloidosis is a progressive disease leading to heart failure with reduced ejection fraction.
- Orthotopic heart transplantation is a treatment option for end-stage heart failure.
- Coronary artery anomalies can occur and may have clinical significance.
Purpose of the Study:
- To report a rare case of anomalous coronary artery anatomy discovered in a donor heart after transplantation.
- To highlight the importance of pre- and post-operative cardiac evaluation.
Main Methods:
- Case report detailing a patient's clinical course.
- Review of diagnostic imaging findings (e.g., coronary angiography, CT angiography).
Main Results:
- A 67-year-old male with cardiac amyloidosis underwent heart transplantation.
- Post-transplant imaging revealed an anomalous left circumflex coronary artery originating from the donor right coronary artery.
- The anomaly was identified in the donor heart's vasculature.
Conclusions:
- Anomalous coronary artery origins can be present in donor hearts, even after transplantation.
- Careful anatomical assessment is crucial in transplant recipients to detect such variations.
- This case underscores the variability of coronary anatomy encountered in cardiac transplantation.
Abstract:
The following case details a 67-year-old male with a history of heart failure with reduced ejection fraction secondary to cardiac amyloidosis who underwent orthotopic heart transplantation and was later found to have an anomalous left circumflex arising from the right coronary artery in the donor heart.


