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Early post-operative fever after colorectal surgery in infants is common and rarely associated with infection
Jacky Z Kwong1, Eveline Lapidus-Krol2, Jacob C Langer2
1Division of Pediatric Surgery, Department of Surgery, Rush University Medical Center, Chicago, IL, USA. jacky_z_kwong@rush.edu.
Insights
Early post-operative fever in infants after colorectal surgery is common and rarely indicates infection. Further research is needed to identify infants requiring investigation versus observation.
Area of Science:
- Pediatric Surgery
- Infectious Disease
- Neonatal Care
Background:
- Early post-operative fever (within 48 hours) is frequent in pediatric patients but often not infection-related.
- Established guidelines for adult post-operative fever evaluation are lacking for infants.
- This study addresses the scarcity of data on pediatric post-operative fever investigation.
Purpose of the Study:
- To determine which infants require investigation for fever after colorectal reconstructive surgery.
- To identify factors associated with infection in infants with early post-operative fever.
Main Methods:
- Retrospective chart review of infants (<1 year) undergoing elective anorectal malformations (ARM) or Hirschsprung Disease (HD) reconstruction.
- Analysis of patient and perioperative characteristics to identify infection risk factors.
- Inclusion of 68 infants (38 HD, 30 ARM) between June 2018 and April 2020.
Main Results:
- 32.4% of infants experienced early post-operative fever.
- Infection was confirmed in only two infants.
- Pre-operative colostomy and longer operative times were linked to increased fever risk (p < 0.05).
Conclusions:
- Early post-operative fever in infants undergoing colorectal surgery is common and seldom infectious.
- Further research is essential to guide appropriate work-up and observation strategies for these infants.
Purpose:
Early post-operative fever (< 48 h) is common in adults and children and seldom indicative of an infection. Guidance to limit excessive evaluation in adults is well-characterized but similar studies for the pediatric population is scarce. This study was performed to better clarify which infants should undergo investigation for post-operative fever after colorectal reconstructive surgical procedures.
Methods:
We performed a retrospective chart review of all infants under one year of age who underwent elective reconstruction for anorectal malformations (ARM) and Hirschsprung Disease (HD) between June 2018 and April 2020 at a single institution. Patient and perioperative characteristics were analyzed to evaluate for possible factors associated with infection.
Results:
Sixty-eight infants met study criteria - 38 (55.9%) had HD and 30 (44.1%) had ARM. Twenty-two infants (32.4%) had early post-operative fever. A definitive infectious cause was identified in only two infants. The presence of a colostomy pre-operatively and longer operative times were associated with increased risk of post-operative fever (62.5% vs. 22.7% and 175 min vs. 150 min respectively, p < 0.05).
Conclusion:
Early post-operative fever in infants after colorectal surgery is common and rarely associated with an infection. Further research is needed to determine which infants require further work-up and which can be safely observed.
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