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Related Concept Videos

Vitamins01:30

Vitamins

2.5K
Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced...
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Role of Skin in Vitamin D Synthesis01:23

Role of Skin in Vitamin D Synthesis

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The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
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Mineral, Vitamin and Water Absorption01:27

Mineral, Vitamin and Water Absorption

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Electrolytes are essential minerals and ions primarily obtained from the diet and absorbed through the gastrointestinal tract. Most electrolytes are absorbed in the small intestine. While the absorption of iron and calcium primarily occurs in the duodenum, calcium is also absorbed in the jejunum and ileum. In these regions, passive diffusion contributes to its absorption alongside active transport mechanisms in the duodenum. These ions can exit the enterocytes through specialized active...
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Role of Vitamins in Maintaining Bone Health01:25

Role of Vitamins in Maintaining Bone Health

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The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
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Anticoagulant Drugs: Vitamin K Antagonists and Direct Oral Anticoagulants01:18

Anticoagulant Drugs: Vitamin K Antagonists and Direct Oral Anticoagulants

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Oral anticoagulants are vital tools in preventing and treating blood clotting disorders. This diverse class of medications can be categorized as vitamin K antagonists, exemplified by warfarin, and direct thrombin inhibitors (DTIs), such as dabigatran, as well as factor Xa inhibitors, including rivaroxaban.
Warfarin, a prominent vitamin K antagonist family member, exerts its effect by inhibiting the enzyme VKORC1 (vitamin K epoxide reductase complex 1). By hindering this enzyme, warfarin...
2.4K
Nursing Clinical Information System01:27

Nursing Clinical Information System

1.3K
Nursing Clinical Information System (NCIS)
A Nursing Clinical Information System (NCIS) is a specialized type of healthcare information system tailored to meet the unique needs of nursing practice. It incorporates the principles of nursing informatics to streamline information management and improve the quality of care delivery.
Critical attributes of NCIS include:
1.3K

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Articles linked to this work by shared authors, journal, and citation graph.

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Vitamin E and human health: rationale for determining recommended intake levels.

Nutrition (Burbank, Los Angeles County, Calif.)·1997
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Ratio of bioavailability of RRR-/all-rac-alpha-tocopherol.

The American journal of clinical nutrition·1995
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Critical assessment of the epidemiological data concerning the impact of antioxidant nutrients on cancer and cardiovascular disease.

Critical reviews in food science and nutrition·1995
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New views on the function and health effects of vitamins.

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Human adipose alpha-tocopherol and gamma-tocopherol kinetics during and after 1 y of alpha-tocopherol supplementation.

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Implications for the biomedical field.

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Related Experiment Video

Updated: Feb 6, 2026

Author Spotlight: Unraveling Vitamin A Transport Mechanisms — Linking Liver Receptors to Vision Health Through RBPR2 and RBP4 Interactions
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Clinical uses of vitamin E.

L J Machlin

    Acta Vitaminologica Et Enzymologica
    |January 1, 1985
    PubMed
    Summary

    Vitamin E supplementation early in life can prevent serious health issues in premature infants and children with liver disease. It also shows benefits for sickle cell anemia, intermittent claudication, and may reduce risks of heart disease and cancer.

    Area of Science:

    • Nutritional Science
    • Pediatrics
    • Hematology

    Background:

    • Vitamin E (tocopherol) plays a crucial role in cellular protection.
    • Deficiency is linked to various health complications, particularly in vulnerable populations.
    • Its therapeutic potential spans neonatal care, chronic diseases, and cardiovascular health.

    Purpose of the Study:

    • To review the multifaceted benefits of early and therapeutic vitamin E administration.
    • To highlight vitamin E's role in preventing and managing specific medical conditions.
    • To explore its impact on hematological, neurological, and cardiovascular parameters.

    Main Methods:

    • Review of studies on vitamin E administration in premature infants, children with cholestatic liver disease, and patients with specific genetic disorders.

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  • Analysis of clinical trials investigating vitamin E's effects on blood disorders, intermittent claudication, and platelet function.
  • Examination of epidemiological data correlating vitamin E levels with disease risk.

    • Main Results:

    • Early vitamin E prevents retinopathy and intraventricular hemorrhage in low birth weight infants.
    • Neurological symptoms in cholestatic liver disease are prevented/reversed if treated before age 3.
    • Vitamin E aids in managing neuropathy, retinopathy, hemolytic anemias, and sickle cell disease.
    • Improved walking distance and blood flow in intermittent claudication patients.
    • Reduced platelet aggregation and enhanced prostacyclin production.
    • Higher vitamin E levels correlate with lower risk of ischemic heart disease, cancer, and infections.

    Conclusions:

    • Vitamin E is a critical nutrient with significant therapeutic applications across a spectrum of diseases.
    • Timely administration is key for optimal outcomes, especially in neonatal and pediatric populations.
    • Further research into its cardioprotective and anti-cancer effects is warranted.