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Evolving approaches in advanced gallbladder cancer with complete pathological response using chemo‑immunotherapy: A
Elena Orlandi1, Ilaria Toscani1, Serena Trubini1
1Department of Oncology-Hematology, Piacenza General Hospital, I-29121 Piacenza, Italy.
Oncology Letters
|August 20, 2024
Summary
Chemo-immunotherapy shows promise for metastatic cholangiocarcinoma (CCA) and gallbladder cancer (GBC), leading to significant tumor reduction and complete responses in some patients. Further research is needed to identify biomarkers for predicting treatment success.
Area of Science:
- Oncology
- Immunotherapy
- Gastrointestinal Cancers
Background:
- Metastatic cholangiocarcinoma (CCA) and gallbladder cancer (GBC) have limited treatment options.
- Chemotherapy combined with immunotherapy demonstrates improved survival and response rates.
- Previous trials like TOPAZ-1 and KEYNOTE-966 established the efficacy of chemo-immunotherapy in GBC.
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