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Updated: Jun 16, 2025

Using Looming Visual Stimuli to Evaluate Mouse Vision
Published on: June 13, 2019
Coupled oscillations orchestrate selective information transmission in visual cortex
Mohammad Bagher Khamechian1,2, Mohammad Reza Daliri1,2, Stefan Treue3,4,5,6
1Neuroscience and Neuroengineering Research Laboratory, Biomedical Engineering Department, School of Electrical Engineering, Iran University of Science and Technology (IUST), Dardasht St., District 8, Tehran 16846-13114, Iran.
Abstract:
Performing visually guided behavior involves flexible routing of sensory information towards associative areas. We hypothesize that in visual cortical areas, this routing is shaped by a gating influence of the local neuronal population on the activity of the same population's single neurons. We analyzed beta frequencies (representing local population activity), high-gamma frequencies (representative of the activity of local clusters of neurons), and the firing of single neurons in the medial temporal (MT) area of behaving rhesus monkeys. Our results show an influence of beta activity on single neurons, predictive of behavioral performance. Similarly, the temporal dependence of high-gamma on beta predicts behavioral performance. These demonstrate a unidirectional influence of network-level neural dynamics on single-neuron activity, preferentially routing relevant information. This demonstration of a local top-down influence unveils a previously unexplored perspective onto a core feature of cortical information processing: the selective transmission of sensory information to downstream areas based on behavioral relevance.
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