Related Experiment Video
Updated: May 6, 2026

Mouse Models for Graft Arteriosclerosis
Published on: May 14, 2013
Antineutrophil Cytoplasmic Antibody Vasculitis after Coronary Artery Bypass Grafting
Dwight D Harris1, Sharif A Sabe1, Afshin Ehsan1
1Division of Cardiothoracic Surgery Department of Surgery Cardiovascular Research Center, Rhode Island Hospital Rhode Island Hospital Alpert Medical School of Brown University, Providence, Rhode Island, USA.
Abstract:
Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis is a group of rare autoimmune disorders associated with the presence of ANCA autoantibodies. We present the first reported case of acute ANCA-associated vasculitis following coronary artery bypass grafting in a 74-year-old male presenting on postoperative day 13 with shortness of breath, orthopnea, and acute kidney injury. Renal biopsy ultimately showed focal necrotizing and crescentic glomerulonephritis, and the patient was successfully managed with corticosteroids and outpatient rituximab. This rare case highlights the importance of having an expanded differential for uncommon causes of cardiovascular disease and unexpected outcomes after coronary artery bypass grafting.
Related Concept Videos
Pericarditis I: Introduction
Coronary Artery Disease I: Introduction
Coronary Artery Disease V: Interprofessional Care
Acute Coronary Syndrome I: Introduction
Acute Coronary Syndrome III: Diagnostic Studies
Peripheral Artery Disease V: Postoperative Nursing Management

