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Talin1 promotes HCC progression by regulating NRG1/PI3K/AKT pathway

Jialong Liu1, Yao Lu1, Bowen Zheng1

  • 1Insititute of Hepatobiliary Surgery, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China.

Discover Oncology
|August 20, 2024
PubMed
Summary

Talin1 protein promotes hepatocellular carcinoma (HCC) progression and metastasis by stabilizing NRG1 mRNA, which activates the PI3K/AKT pathway. Inhibiting Talin1 offers a potential therapeutic strategy for HCC treatment.

Keywords:
AKTHepatocellular carcinomaNRG1PI3KTalin1

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