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Treatment of Tuberculous Pleurisy With Contezolid in a Child With Glucose-6-Phosphate Dehydrogenase Deficiency: The

Shaolan Shi1, Binbin Feng, Dan Li

  • 1From the Department of Tuberculosis Medicine Three wards, Shandong Public Health Clinical Center, Jinan, China.

The Pediatric Infectious Disease Journal
|August 20, 2024
PubMed

Insights

This study reports the first pediatric case of tuberculous pleurisy and glucose-6-phosphate dehydrogenase deficiency treated with contezolid. The patient showed a positive response without adverse events, suggesting contezolid as a potential treatment option.

Area of Science:

  • Pediatric infectious diseases
  • Pharmacology
  • Genetics

Background:

  • Tuberculous pleurisy is a significant global health concern, particularly in pediatric populations.
  • Glucose-6-phosphate dehydrogenase (G6PD) deficiency presents challenges in drug selection due to potential hemolytic anemia.
  • Limited treatment options exist for complicated pediatric tuberculous pleurisy, especially with co-existing genetic conditions.

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