Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Myocarditis I: Introduction01:21

Myocarditis I: Introduction

605
Myocarditis is inflammation of the myocardium, which is the muscular layer of the heart.EtiologyMyocarditis has a diverse etiology, including a wide range of infectious and non-infectious causes:Infectious CausesViral: Common viruses include Coxsackie A and B, adenovirus, parvovirus B19, enteroviruses, and influenza A.Bacterial: Examples include infections caused by Streptococcus, Staphylococcus, and Mycoplasma species.Rickettsial: Infections like Rocky Mountain spotted fever can result in...
605
Myocarditis II: Clinical Features and Diagnostic Tests01:27

Myocarditis II: Clinical Features and Diagnostic Tests

453
Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
453
Myocarditis III: Medical Management01:14

Myocarditis III: Medical Management

327
Myocarditis: Comprehensive Medical ManagementMyocarditis, the heart muscle inflammation, requires a comprehensive medical management strategy that addresses the underlying cause, provides supportive care, manages symptoms, and reduces cardiac workload.Infections and Autoimmune CausesAdminister appropriate antimicrobial therapy when an infectious agent causes myocarditis. For instance, penicillin treats infections caused by Group A Streptococcus. In cases where autoimmune processes are...
327
Myocarditis IV: Nursing Management01:22

Myocarditis IV: Nursing Management

367
Myocarditis is an inflammatory condition of the myocardium requiring meticulous nursing management for optimal patient outcomes. Effective management begins with a thorough assessment of the patient's medical history, paying close attention to past infections, autoimmune disorders, travel history, and exposure to toxins or drugs. Recent viral infections and systemic diseases are particularly relevant due to their potential role in triggering myocarditis.Physical Examination and MonitoringThe...
367
Diphtheria01:28

Diphtheria

103
Diphtheria is an acute, toxin-mediated infectious disease that primarily affects the upper respiratory tract. It is caused by Corynebacterium diphtheriae, a Gram-positive, pleomorphic rod that lacks spore-forming capability and exhibits a characteristic club-shaped morphology under microscopic examination. While C. diphtheriae can asymptomatically colonize mucosal surfaces, clinical disease manifests only when the bacterial strain is lysogenized by a specific β-corynephage. This phage...
103
Influenza01:27

Influenza

51
Influenza is an acute, highly communicable viral disease that affects the respiratory tract and is responsible for seasonal epidemics worldwide. Influenza A is the most prevalent type associated with widespread outbreaks and is subtyped based on two surface glycoproteins: hemagglutinin (H) and neuraminidase (N), as in H1N1. These glycoproteins are essential for viral infectivity, transmission, and immune recognition. Transmission occurs primarily through respiratory droplets and contaminated...
51

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Two-year neurodevelopmental outcome in preterm neonates with cerebral oxygenation monitoring after birth: a multinational, multicenter retrospective follow-up study of the COSGOD III trial.

Frontiers in pediatrics·2026
Same author

Isolated prenatal foramen ovale closure or restriction presenting after birth: a distinct, under-recognized clinical condition.

Frontiers in pediatrics·2026
Same author

Neurodevelopmental outcome up to 5 Years after Isolated Mild Non-Cystic White Matter Injury in Very Preterm Infants.

Neonatology·2026
Same author

Perinatal arterial ischemic stroke - Is amplitude integrated EEG a helpful tool for the clinician?

Early human development·2026
Same author

Effects of a Prolonged Exclusive Human Milk-Based Diet on Structural and Functional Brain Maturation in Very Preterm Infants: An Ancillary Analysis of the NEOVASC Trial.

Nutrients·2026
Same author

Cardiovascular Health Was Moderate in Austrian Adolescents and Showed an Inverse Relationship With High-Sensitivity C-Reactive Protein Levels.

Acta paediatrica (Oslo, Norway : 1992)·2026
Same journal

A 14-Year-old Girl With Neurologic Decline and Unexpected CSF Findings.

The Pediatric infectious disease journal·2026
Same journal

Model-based Differentiation Between Kawasaki Disease and MIS-C: The Importance of the Mitral Valve.

The Pediatric infectious disease journal·2026
Same journal

Pulmonary Embolism in Invasive Salmonella Infection: A Rare Cause of Acute Respiratory Failure in an Adolescent.

The Pediatric infectious disease journal·2026
Same journal

Phase 2/3, Open-label, Randomized, Active-controlled Clinical Trial Evaluating the Safety and Efficacy of Imipenem/Cilastatin/Relebactam in Pediatric Patients From Birth to Less Than 18 Years With Gram-negative Bacterial Infections.

The Pediatric infectious disease journal·2026
Same journal

Determinants of Severity in Pediatric Viral Lower Respiratory Tract Diseases From Emergency Department Presentation to Hospital Course.

The Pediatric infectious disease journal·2026
Same journal

Oropharyngeal Colonization by Kingella kingae and Septic Arthritis in Children 6-48 Months of Age: A Portuguese Multicenter Case-control Study.

The Pediatric infectious disease journal·2026
See all related articles

Related Experiment Video

Updated: Apr 11, 2026

Using Bioluminescent Imaging to Investigate Synergism Between Streptococcus pneumoniae and Influenza A Virus in Infant Mice
10:47

Using Bioluminescent Imaging to Investigate Synergism Between Streptococcus pneumoniae and Influenza A Virus in Infant Mice

Published on: April 14, 2011

16.8K

Fatal Neonatal Influenza A Myocarditis.

Elisabeth Ralser1, Christina Edwards2, Michaela Höck1

  • 1From the Department of Pediatrics II (Neonatology).

The Pediatric Infectious Disease Journal
|August 20, 2024
PubMed
Summary
This summary is machine-generated.

A newborn experienced fatal resuscitation due to fetal myocarditis. Influenza A infection during pregnancy was identified as the cause in this case study.

More Related Videos

Myocardial Infarction in Neonatal Mice, A Model of Cardiac Regeneration
07:48

Myocardial Infarction in Neonatal Mice, A Model of Cardiac Regeneration

Published on: May 24, 2016

18.5K
Intracerebroventricular and Intravascular Injection of Viral Particles and Fluorescent Microbeads into the Neonatal Brain
05:51

Intracerebroventricular and Intravascular Injection of Viral Particles and Fluorescent Microbeads into the Neonatal Brain

Published on: July 24, 2016

19.4K

Related Experiment Videos

Last Updated: Apr 11, 2026

Using Bioluminescent Imaging to Investigate Synergism Between Streptococcus pneumoniae and Influenza A Virus in Infant Mice
10:47

Using Bioluminescent Imaging to Investigate Synergism Between Streptococcus pneumoniae and Influenza A Virus in Infant Mice

Published on: April 14, 2011

16.8K
Myocardial Infarction in Neonatal Mice, A Model of Cardiac Regeneration
07:48

Myocardial Infarction in Neonatal Mice, A Model of Cardiac Regeneration

Published on: May 24, 2016

18.5K
Intracerebroventricular and Intravascular Injection of Viral Particles and Fluorescent Microbeads into the Neonatal Brain
05:51

Intracerebroventricular and Intravascular Injection of Viral Particles and Fluorescent Microbeads into the Neonatal Brain

Published on: July 24, 2016

19.4K

Area of Science:

  • Perinatology
  • Virology
  • Pediatric Pathology

Background:

  • A term infant required emergency resuscitation in the delivery room, which proved unsuccessful.
  • The mother reported a common cold during the third trimester of pregnancy.
  • Antenatal examinations were otherwise unremarkable.

Purpose of the Study:

  • To investigate the cause of unexpected fetal demise and the failure of resuscitation.
  • To identify potential links between maternal illness and fetal complications.

Main Methods:

  • Clinical case review of a term neonate.
  • Autopsy examination of the deceased infant.
  • Histopathological analysis for infectious agents.

Main Results:

  • The infant's heart rate remained critically low (15-20 beats/minute) despite resuscitation.
  • Autopsy revealed fetal myocarditis.
  • Influenza A viral infection was confirmed as the cause of myocarditis.

Conclusions:

  • Influenza A infection in the mother during late pregnancy can lead to severe fetal myocarditis.
  • Fetal myocarditis may result in stillbirth or neonatal death, even with prompt resuscitation.
  • This case highlights the importance of considering maternal viral infections in unexplained fetal or neonatal deaths.