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Multiple organ procurement from one donor.

R F Brodman, F J Veith, J Goldsmith

    The Journal of Heart Transplantation
    |February 1, 1985
    PubMed
    Summary
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    This study shows that retrieving multiple organs, including the heart and lungs, from a single donor for separate transplantation is feasible. This approach maximizes organ utilization for transplantation into multiple recipients.

    Area of Science:

    • Cardiovascular Surgery
    • Thoracic Surgery
    • Transplantation Medicine

    Background:

    • Maximizing organ utilization is crucial in transplantation.
    • Current methods may not fully leverage all viable organs from a single donor.

    Purpose of the Study:

    • To assess the feasibility of retrieving the heart and lungs as separate organs or blocks for multi-recipient transplantation.
    • To evaluate techniques for organ retrieval and preservation.

    Main Methods:

    • Excision of heart-lung blocks or single lungs in canine models, followed by six hours of lung preservation.
    • Retrieval of three separate organs or heart and bilateral lung blocks in human cadavers.
    • Utilizing left atrial wall division for individual organ transplantation.

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    Main Results:

    • Successful transplantation of four preserved lungs and eight hearts in canine models.
    • Satisfactory retrieval of organs for multi-recipient transplantation in human cadavers.
    • Demonstrated suitability of atrial wall division for individual organ cuffs.

    Conclusions:

    • Multiple organ donation from a single donor is feasible.
    • Separate organ transplantation of retrieved heart and lungs can be achieved.
    • This technique enhances organ utilization for transplantation.