A comprehensive analysis of renal DTPA studies. II. Renal transplant evaluation

Renal transplant radionuclide studies, using DTPA, were analysed to produce flow and transit time measurements in both the initial arterial phase, and the later glomerular phase. Results are presented for transplanted kidneys which are normal, infarcted, obstructed, or suffering from rejection or acute tubular necrosis. Sequential studies of the vascular flow and transit time indices showed considerable promise in the detection of acute rejection, even in the presence of acute tubular necrosis. Of the six numerical indices to demonstrate acute rejection, five had accuracies of 74% or more, and all three of the indices which compared a study with a previous one had accuracies of 83% or more.