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Published on: March 14, 2017
[Thyrotoxic periodic paralysis]
Ai Phi Thuy Ho1, Eirik Brekka Tjønnfjord2, Ragnar Bekkhus Moe3
1Avdeling for hjertesykdommer, Sykehuset Østfold Kalnes.
Background:
Thyrotoxic periodic paralysis is a rare and serious complication of hyperthyroidism.
Case Presentation:
A man in his thirties of Asian descent, with non-compliant Graves' disease, presented with extremity paresis. Emergency blood tests revealed severe hypokalaemia, leading to a diagnosis of thyrotoxic periodic paralysis. The combination of uncontrolled hyperthyroidism, Asian ethnicity, paralysis, and severe hypokalaemia without other causes defined the diagnosis. Acute treatment involves non-selective beta-blockers, addressing hyperthyroidism, and potassium supplements.
Interpretation:
Swift recognition of thyrotoxic periodic paralysis is crucial for timely and life-saving treatment. If triggered by hyperthyroidism, as in Graves' disease, surgery or radioiodine is strongly indicated for definitive treatment. It is noteworthy that euthyroid patients cannot develop thyrotoxic periodic paralysis.
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