SURGICAL OUTCOMES IN CONCURRENT SICKLE CELL AND DIABETIC RETINOPATHY.
Landon J Rohowetz1, Abdulla Shaheen1, Maria Magraner1
1Department of Ophthalmology, Bascom Palmer Eye Institute, Miami, Florida; and.
Retina (Philadelphia, Pa.)
|August 21, 2024
Summary
Vitreoretinal surgery for concurrent sickle cell retinopathy and diabetic retinopathy showed poor visual and anatomic outcomes. Preoperative vision was the strongest predictor of final visual acuity in retinal detachment cases.
Area of Science:
- Ophthalmology
- Retinal Surgery
- Medical Complications
Background:
- Sickle cell retinopathy and diabetic retinopathy are leading causes of vision loss.
- Concurrent presentation poses unique surgical challenges.
- Limited data exists on surgical outcomes for combined retinopathy.
Purpose of the Study:
- To evaluate clinical features and surgical outcomes.
- Focus on eyes with co-existing sickle cell and diabetic retinopathy.
- Assess functional and anatomic results post-vitreoretinal surgery.
Main Methods:
- Retrospective case series (2014-2021).
- Included 20 eyes from 14 patients undergoing vitreoretinal surgery.
- Pars plana vitrectomy was the primary surgical approach.
Main Results:
- Tractional retinal detachment was the most common indication (60%).
- No significant change in best-corrected visual acuity (BCVA) post-surgery.
- Anatomic success achieved in 65% of retinal detachment cases.
Conclusions:
- Surgical outcomes for concurrent sickle cell and diabetic retinopathy are generally poor.
- Preoperative BCVA is a key predictor of postoperative vision in retinal detachment.
- Further research needed for improved management strategies.
More Related Videos
Related Concept Videos
Complications of Diabetes Mellitus
Diabetes mellitus is a chronic metabolic disorder characterized by persistent hyperglycemia due to insulin deficiency, resistance, or both. Prolonged hyperglycemia disrupts metabolic homeostasis and leads to acute and chronic complications.Acute ComplicationsAcute complications result from sudden metabolic imbalance.Diabetic ketoacidosis (DKA) mainly appears in type 1 diabetes but may also develop in type 2 diabetes, particularly under extreme stress. It arises from severe insulin deficiency,...
Diabetic Foot Ulcer
Definition A diabetic foot ulcer (DFU) is a chronic, non-healing wound that develops in individuals with diabetes. It typically occurs on pressure-bearing areas such as the heel, metatarsal heads, or hallux, and carries a high risk of infection and amputation.Pathophysiology • The development of DFUs can be explained by four interconnected mechanisms: neuropathy, ischemia, infection, and impaired wound healing. • Neuropathy is the most common factor. Sensory neuropathy reduces pain perception,...
Diabetic Retinopathy
DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...
Diabetic Nephropathy
Definition Diabetic nephropathy is a chronic kidney complication that results from prolonged hyperglycemia.Prevalence It is the most common cause of chronic kidney disease (CKD) and end-stage renal disease (ESRD) worldwide, affecting up to half of individuals with diabetes.Pathophysiology • Sustained hyperglycemia triggers multiple hemodynamic and metabolic changes in the kidney. • Early in the disease, increased renal blood flow and glomerular hyperfiltration occur due to afferent arteriolar...


