Food biodiversity and gastrointestinal cancer risk in nine European countries: Analysis within a prospective cohort study
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View abstract on PubMed
Summary
This summary is machine-generated.Increasing dietary species richness may reduce the risk of certain gastrointestinal cancers. This study found greater food biodiversity was linked to lower cancer incidence in a large European population.
Area Of Science
- Nutritional Epidemiology
- Gastroenterology
- Oncology
Background
- Dietary biodiversity offers potential public health and sustainability benefits.
- Limited evidence exists on the link between food biodiversity and cancer, especially gastrointestinal cancers.
- This study investigates dietary species richness (DSR) and gastrointestinal cancer risk.
Purpose Of The Study
- To evaluate the association between dietary species richness (DSR) and gastrointestinal cancer risk.
- To assess the impact of food biodiversity on cancer development in a pan-European cohort.
Main Methods
- Analysis of 450,111 adults from the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort.
- Dietary intakes assessed via country-specific questionnaires; DSR calculated from unique species in food/drink items.
- Multivariable Cox proportional hazards regression models used to examine associations between DSR and cancer risk.
Main Results
- Over 14.1 years median follow-up, 10,705 gastrointestinal cancer cases were diagnosed.
- Higher DSR was inversely associated with overall gastrointestinal cancer risk (HR: 0.77; 95% CI: 0.69-0.87).
- Inverse associations observed for oesophageal squamous cell carcinoma, proximal colon, colorectal, and liver cancer.
Conclusions
- Greater dietary food biodiversity may decrease the risk of specific gastrointestinal cancers.
- Further research is recommended to confirm these findings and elucidate underlying mechanisms.
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