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Related Experiment Video

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Stigmatization and Preferences in Monkeypox Vaccine Regimens.

Yi-Hsuan Shen1, Hao-Hsiang Chang2,3, Chiao-Yun Tou2

  • 1Department of Dermatology, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan.

Archives of Sexual Behavior
|August 21, 2024
PubMed
Summary

Monkeypox (mpox) vaccination site choice is influenced by stigma. Forearm intradermal injections caused more adverse events, leading individuals to prefer deltoid vaccinations to avoid visible marks and social judgment.

Keywords:
LGBTQ+Men who have sex with menMonkeypoxSexual and gender minoritiesStigmaVaccine

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Area of Science:

  • Public Health
  • Immunology
  • Social Science

Background:

  • The 2022 monkeypox (mpox) outbreak disproportionately affected sexual and gender minority (SGM) groups.
  • Stigma associated with mpox and SGM identity created hesitancy towards vaccination, particularly regarding injection site concerns.

Purpose of the Study:

  • To investigate the physical and psychological impacts of different mpox vaccination regimens.
  • To identify factors influencing vaccinee preferences for injection sites, considering potential stigma.

Main Methods:

  • An online survey was conducted among 2,827 adults receiving their second mpox pre-exposure vaccination in Taiwan.
  • Questionnaires assessed adverse events from the first vaccination and preferences for the second, including influencing factors.

Main Results:

  • Intradermal forearm injections were linked to increased physical (e.g., discoloration) and psychological adverse events.
  • Concerns about "beauty," "scar," and "others' view" significantly influenced vaccination site preferences.
  • Participants prioritizing "others' views" were more likely to prefer deltoid vaccinations over forearm injections.

Conclusions:

  • Mpox vaccination site preferences are significantly associated with stigma and the desire to avoid visible adverse effects.
  • Understanding these preferences is crucial for mitigating vaccinee distress and improving public health strategies for mpox immunization.