Comparative outcomes of mechanical and transepithelial PRK on the same excimer laser: A contralateral eye study

PurposeCompare refractive results between mechanical PRK (mPRK) and transepithelial PRK (tPRK) with WaveLight Allegretto EX500 excimer laser system (Alcon Laboratories, Fort Worth, TX, USA).SettingDepartment of Ophthalmology of the Federal University of Sao Paulo, Brazil.DesignProspective and randomized study.MethodsIn 151 eyes of 73 patients with astigmatism and myopia, both eyes had similar refraction before surgery, with a maximum of 15-µm difference in ablation who underwent mPRK in one eye and tPRK in the contralateral eye. The mean age of the patients in this study was 31.45 ± 6.97 years (range, 22 to 54 years).ResultsA comparison was made with all variables between the two groups, and we found that UDVA and SE were worse in the tPRK group at six months than in the mPRK group. In the mPRK group, there was a higher frequency in the +/- 0.50 range and a lower frequency in the +/- 1.50 range. In the tPRK group, however, there was a lower frequency in the +/- 0.50 range and a higher frequency in the +/- 1.50 range. Concerning gain or loss of lines of sight, there was no association between the two groups (chi-square test, p = 0.887).ConclusionBoth mPRK and tPRK appear to have similar safety. However, mPRK was associated with significantly better UDVA and SE six months post-operatively.