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Utilizing omics technologies in the investigation of sepsis-induced cardiomyopathy
Zheng Han1, Zhen Quan1, Siyao Zeng1
1Harbin Medical University Graduate School, Harbin Medical University, Heilongjiang Province, Harbin 150086, China.
Abstract:
Sepsis-induced cardiomyopathy (SIC) is a common and high-mortality complication among critically ill patients. Uncertainties persist regarding the pathogenesis, pathophysiology, and diagnosis of SIC, underscoring the necessity to investigate potential biological mechanisms. With the rise of omics technologies, leveraging their high throughput and big data advantages, a systems biology perspective is employed to study the biological processes of SIC. This approach aids in gaining a better understanding of the disease's onset, progression, and outcomes, ultimately providing improved guidance for clinical practices. This review summarizes the currently applied omics technologies, omics studies related to SIC, and relevant omics databases.
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