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D-dimer assay interference detected by the discrepancy in D-dimer concentrations at different dilutions: a case

Marija Milić1,2, Dejana Brkić Barbarić3, Iva Lukić1,2

  • 1Clinical Institute of Laboratory Diagnostics, University Hospital Centre Osijek, Osijek, Croatia.

Biochemia Medica
|August 22, 2024
PubMed
Summary

Heterophilic antibodies can interfere with D-dimer testing, leading to inaccurate results. This case report details how SARS-CoV-2 infection may cause such interference, necessitating careful laboratory investigation and clinical-laboratory collaboration.

Keywords:
D-dimerblood coagulation testsheterophile antibodiesinterference

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