Related Experiment Video
Updated: Jun 15, 2025
A Novel Microsurgical Model for Heterotopic, En Bloc Chest Wall, Thymus, and Heart Transplantation in Mice
Published on: January 23, 2016
Micro-transplantation in an elderly patient with very high risk MDS:A case report and literature review
Kangli Wu1, Mingsuo Liu1, Yajun Wu1
1Department of hematology, Yiwu Central Hospital, Yiwu, Zhejiang Province, 322099, China.
Introduction:
The prognosis of patients with myelodysplastic syndromes (MDS) (very high risk) is poor.HLA-mismatched allogeneic T-cell infusion which is called micro-transplantation can not only shorten the time of bone marrow suppression, but also improve the treatment response of patients.
Case Presentation:
A 74-year-old woman presented with fatigue and showed pancytopenia on routine blood count. She was diagnosed with MDS (very high risk) after bone marrow examination,then she received 4 cycles of micro-transplantation. The progression-free survival was 22 months and overall survival was 33 months.
Discussion:
The patient showed good tolerance to micro-transplantation with manageable toxicities and short myelosuppression time.
Related Concept Videos
01:22Bone Marrow Sampling and Transplants
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
01:24Tissue Transplantation
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...