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AI-enhanced "Two-thirds Guidelines" for Lipolifting: Addressing Multiple Hallmarks of Facial Aging.

Kemal Tunç Tiryaki1, Serli Canikyan2, Jack Woods1

  • 1From the Department of Plastic and Reconstructive Surgery, Cadogan Clinic, London, United Kingdom.

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Summary

The two-thirds guidelines offer a novel approach to facial fat grafting for rejuvenation, improving outcomes for aging signs like volume loss. This method enhances natural results and minimizes risks for patients seeking facial restoration.

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Area of Science:

  • Plastic Surgery
  • Aesthetic Medicine
  • Regenerative Medicine

Background:

  • Facial aging is characterized by volume loss, ligament weakening, and altered skin quality.
  • The "two-thirds guidelines" represent a new strategy for facial rejuvenation.
  • These guidelines are derived from an analysis of 2800 facial fat grafting procedures over 20 years.

Purpose of the Study:

  • To develop a systematic framework for multilayer fat rejuvenation and ligament restoration using facial lipolifting data.
  • To establish specific guidelines for microfat and nanofat injections based on patient age and facial regions.
  • To evaluate the efficacy and applicability of the "two-thirds guidelines" in facial fat grafting.

Main Methods:

  • Analysis of 2800 facial fat grafting procedures, including patient age, fat type (microfat, nanofat), and injection depth.
  • Development of the "two-thirds guidelines": two-thirds of patient's age for microfat and one-third for nanofat.
  • Prospective study of 400 patients to confirm guideline efficacy, with consideration for facial proportions and body mass index.

Main Results:

  • The "two-thirds guidelines" demonstrated efficacy in a prospective study of 400 patients.
  • Patients within the golden ratio (1.4-1.9) reported high satisfaction, 50% fat graft uptake, and minimal complications.
  • Applicability may vary for patients outside standard deviation ranges; an AI program was developed for such cases.

Conclusions:

  • The "two-thirds guidelines" provide a comprehensive, safe, and adaptable approach to facial rejuvenation via fat grafting.
  • This method addresses volume loss, ligament weakening, and skin quality, offering natural and enduring outcomes.
  • The guidelines can be used standalone or with facelift techniques, minimizing overfilling risks and informing AI development for clinical support.