Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Surface Tension, Capillary Action, and Viscosity02:57

Surface Tension, Capillary Action, and Viscosity

27.6K
Surface Tension
The various IMFs between identical molecules of a substance are examples of cohesive forces. The molecules within a liquid are surrounded by other molecules and are attracted equally in all directions by the cohesive forces within the liquid. However, the molecules on the surface of a liquid are attracted only by about one-half as many molecules. Because of the unbalanced molecular attractions on the surface molecules, liquids contract to form a shape that minimizes the number...
27.6K
Comparing Intermolecular Forces: Melting Point, Boiling Point, and Miscibility02:34

Comparing Intermolecular Forces: Melting Point, Boiling Point, and Miscibility

44.2K
Intermolecular forces are attractive forces that exist between molecules. They dictate several bulk properties, such as melting points, boiling points, and solubilities (miscibilities) of substances. Molar mass, molecular shape, and polarity affect the strength of different intermolecular forces, which influence the magnitude of physical properties across a family of molecules.
Temporary attractive forces like dispersion are present in all molecules, whether they are polar or nonpolar. They...
44.2K
Surface Tension of Fluid01:22

Surface Tension of Fluid

255
Surface tension is a fundamental property of fluids, occurring at the boundary between a liquid and a gas or between two immiscible liquids. This phenomenon arises from the cohesive forces between molecules at the fluid's surface, creating an effect similar to a stretched elastic membrane. Inside each fluid, molecules are equally attracted in all directions by neighboring molecules, but surface molecules experience a net inward force, resulting in surface tension.
Surface tension varies...
255
Frictional Force01:07

Frictional Force

7.8K
When a body is in motion, it encounters resistance because the body interacts with its surroundings. This resistance is known as friction, a common yet complex force whose behavior is still not completely understood. Friction opposes relative motion between systems in contact, but also allows us to move. Friction arises in part due to the roughness of surfaces in contact. For one object to move along a surface, it must rise to where the peaks of the surface can skip along the bottom of the...
7.8K
Membrane Fluidity01:23

Membrane Fluidity

151.7K
Cell membranes are composed of phospholipids, proteins, and carbohydrates loosely attached to one another through chemical interactions. Molecules are generally able to move about in the plane of the membrane, giving the membrane its flexible nature called fluidity. Two other features of the membrane contribute to membrane fluidity: the chemical structure of the phospholipids and the presence of cholesterol in the membrane.
151.7K
Contact Angle01:13

Contact Angle

12.3K
When a solid is dipped inside a liquid, the liquid surface becomes curved near the contact. For some solid–liquid interfaces, the liquid is pulled up along the solid, while for others, the liquid surface is convex or depressed near the solid surface. This phenomenon can be explained using the concept of cohesive and adhesive forces.
The adhesive force is the molecular force between molecules of different materials, that is, between the molecules of the solid and the liquid. The cohesive...
12.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Revisiting what we lose by coarse-graining: Modeling cooperative hydrophobic phenomena with short-ranged, pair-additive forces.

The Journal of chemical physics·2026
Same author

Correlating solvation shell dynamics and ion transport in highly ordered nanoporous polymers.

Nature communications·2026
Same author

Engineering Antifreeze Proteins to Optimally Resist Engulfment by Ice.

The journal of physical chemistry. B·2026
Same author

The vibrational relaxation of a charged solute probes the vibrational density of states at oxide/water interfaces.

The Journal of chemical physics·2026
Same author

Octahedral tilting and B-site off-centering in halide perovskites are not coupled.

Nature communications·2026
Same author

Delivery of peptide coacervates to form stable interaction hubs in cells.

Nature communications·2026
Same journal

Divergent Aggregation Pathways of DNA-AuNPs: Non-Watson-Crick Assembly Mediated by Structurally Diverse Electrolytes.

The journal of physical chemistry. B·2026
Same journal

Assessing Fluoroacetate Defluorination Potential across Diverse Enzymes Using Quantum Chemistry.

The journal of physical chemistry. B·2026
Same journal

Na<b><sup>+</sup></b> Solvation and Association in Na(SO<sub>3</sub>CF<sub>3</sub>)-Dimethoxyethane Electrolytes by Large-Angle X-Ray Scattering and DFT Calculations.

The journal of physical chemistry. B·2026
Same journal

Donor-Acceptor Separation Augments Temperature Dependence of Kinetic Isotope Effects in NADH Model Hydride Transfer Reactions: Mimicking Enzyme versus Mutant Dynamics.

The journal of physical chemistry. B·2026
Same journal

Disordered Worm-Like Clusters in a Hexagonal Mesophase Former: Simulation and Thermodynamic Description.

The journal of physical chemistry. B·2026
Same journal

Comparative Biophysical Analysis of Healthy and Inflamed Intestinal Membrane Models Using Langmuir Monolayers.

The journal of physical chemistry. B·2026
See all related articles

Related Experiment Video

Updated: Jun 15, 2025

A Microfluidic Approach for the Study of Ice and Clathrate Hydrate Crystallization
08:01

A Microfluidic Approach for the Study of Ice and Clathrate Hydrate Crystallization

Published on: August 18, 2022

3.0K

Interfacial Ice Density Fluctuations Inform Surface Ice-Philicity.

Zachariah Vicars1, Jeongmoon Choi1, Sean M Marks1

  • 1Department of Chemical and Biomolecular Engineering, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.

The Journal of Physical Chemistry. B
|August 22, 2024
PubMed
Summary
This summary is machine-generated.

Surface ice-philicity, the preference for ice over water, is linked to ice-like density fluctuations. This study uses molecular simulations to quantify ice-philicity, revealing how surface structure influences ice binding, even for complex proteins.

More Related Videos

Orientational Transition in a Liquid Crystal Triggered by the Thermodynamic Growth of Interfacial Wetting Sheets
06:26

Orientational Transition in a Liquid Crystal Triggered by the Thermodynamic Growth of Interfacial Wetting Sheets

Published on: May 15, 2017

7.1K
Determining the Ice-binding Planes of Antifreeze Proteins by Fluorescence-based Ice Plane Affinity
08:46

Determining the Ice-binding Planes of Antifreeze Proteins by Fluorescence-based Ice Plane Affinity

Published on: January 15, 2014

9.1K

Related Experiment Videos

Last Updated: Jun 15, 2025

A Microfluidic Approach for the Study of Ice and Clathrate Hydrate Crystallization
08:01

A Microfluidic Approach for the Study of Ice and Clathrate Hydrate Crystallization

Published on: August 18, 2022

3.0K
Orientational Transition in a Liquid Crystal Triggered by the Thermodynamic Growth of Interfacial Wetting Sheets
06:26

Orientational Transition in a Liquid Crystal Triggered by the Thermodynamic Growth of Interfacial Wetting Sheets

Published on: May 15, 2017

7.1K
Determining the Ice-binding Planes of Antifreeze Proteins by Fluorescence-based Ice Plane Affinity
08:46

Determining the Ice-binding Planes of Antifreeze Proteins by Fluorescence-based Ice Plane Affinity

Published on: January 15, 2014

9.1K

Area of Science:

  • Surface science
  • Computational chemistry
  • Biophysics

Background:

  • Surface ice-philicity governs ice nucleation and binding, but its relationship with surface features is poorly understood, especially for heterogeneous surfaces like proteins.
  • Analogous to hydrophobicity studies, ice-philic surfaces may exhibit enhanced ice-like density fluctuations.
  • Characterizing ice-philicity is crucial for understanding ice interactions in biological and material systems.

Purpose of the Study:

  • To investigate the link between surface properties and ice-philicity using molecular simulations.
  • To establish a quantitative measure for ice-philicity based on interfacial ice-density fluctuations.
  • To characterize the ice-philicity of both model surfaces and complex biological molecules, such as antifreeze proteins.

Main Methods:

  • Molecular simulations and enhanced sampling techniques were employed.
  • A family of model surfaces with varying wetting coefficients (k) was analyzed.
  • Interfacial ice-density fluctuations were used as a metric for ice-philicity.

Main Results:

  • The free energy of ice-density fluctuations decreases monotonically with increasing wetting coefficient (k).
  • For fcc systems, the (110) surface demonstrated higher ice-philicity than (111) or (100) surfaces due to topographical complementarity with ice basal planes.
  • The ice-binding site (IBS) of the spruce budworm antifreeze protein (sbwAFP) showed enhanced ice-density fluctuations, indicating higher ice-philicity compared to non-binding sites (NBSs).

Conclusions:

  • Interfacial ice-like fluctuations serve as a reliable measure for surface ice-philicity.
  • The study provides a method to characterize the ice-philicity of heterogeneous surfaces, including proteins.
  • Findings elucidate the molecular basis of ice-surface interactions and offer insights for designing ice-interacting materials.