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Long-wavelength triggered iridium(III) complex nanoparticles for photodynamic therapy against hypoxic cancer
Shengnan Liu1, Ziwei Wang1, Zihan Wu1
1Key Laboratory of Nanobiosensing and Nanobioanalysis at Universities of Jilin Province, Department of Chemistry, Northeast Normal University, 5268 Renmin Street, Changchun, Jilin Province 130024, P. R. China. zhudx047@nenu.edu.cn.
Chemical Communications (Cambridge, England)
|August 22, 2024
Abstract:
A long-wavelength triggered cationic iridium(III) complex, Ir5, and its corresponding nanoparticles with the ability to generate type I and type II reactive oxygen species have been synthesised. The complex targets mitochondria and achieves an excellent photodynamic therapy effect in hypoxic cancer cells.
