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Updated: Jun 15, 2025
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Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease
Published on: December 18, 2016
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Current approach to muscle imaging in myositis
Didem Saygin1, Jemima Albayda2
1Department of Medicine, Division of Rheumatology, Rush University.
Current Opinion in Rheumatology
|August 22, 2024
Summary
Idiopathic inflammatory myopathies (IIM) benefit from muscle imaging. Muscle MRI is the gold standard, while ultrasound and PET scans show promise for monitoring disease activity and extra-muscular findings.
Area of Science:
- Neurology
- Radiology
- Immunology
Background:
- Idiopathic inflammatory myopathies (IIM) require accurate diagnostic tools.
- Muscle imaging aids in diagnosis, biopsy site selection, and distinguishing disease activity from damage.
Purpose of the Study:
- To review the current applications and recent advancements in muscle imaging for IIM.
- To discuss the roles of muscle MRI, ultrasound (US), and PET scans in IIM management.
Main Methods:
- Review of current literature on muscle imaging modalities in IIM.
- Analysis of diagnostic and monitoring capabilities of MRI, US, and PET scans.
Main Results:
- Muscle MRI demonstrates strong correlation with histopathology and is a valuable tool for IIM evaluation.
- Muscle US shows potential as a point-of-care tool for monitoring active myositis.
- FDG-PET scans reveal inflammatory activity in IIM and aid in detecting extra-muscular manifestations and cancers.
Conclusions:
- Muscle MRI is the established gold standard for imaging in IIM.
- Emerging evidence supports the utility of muscle US and PET scans in the comprehensive evaluation and management of IIM.
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