Left ventricular diastolic dysfunction in non-myocardial disorders
Otto A Smiseth1, Tom Kai Ming Wang2, Allan L Klein2
1Division of Cardiovascular and Pulmonary Diseases, Institute for Surgical Research, Oslo University Hospital, University of Oslo, Rikshospitalet, PO Box 4950 Nydalen, NO-0424 Oslo, Norway.
Abstract:
This article reviews and discusses non-myocardial disorders that represent diagnostic challenges when evaluating patients for suspected heart failure with preserved left ventricular ejection fraction. This includes pre-capillary pulmonary hypertension, which is important to differentiate from post-capillary hypertension caused by left-sided heart disease. The impact of electrical disorders on LV diastolic function is also reviewed, and includes a discussion of left bundle branch, which has both a direct effect on LV diastolic function, as well as a long-term effect due to remodelling. Furthermore, evaluation of diastolic function in patients with atrial fibrillation is discussed. Pericardial diseases are reviewed as well as effects of a normal pericardium on diastolic function in failing hearts. Finally, the article reviews how valvular diseases impact LV diastolic function.
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