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Updated: Jun 15, 2025

A Lateralized Odor Learning Model in Neonatal Rats for Dissecting Neural Circuitry Underpinning Memory Formation
Published on: August 18, 2014
The lateral septum returns to the center stage of brain reward
Jonathan J Chow1, Rajtarun Madangopal1, Yavin Shaham1
1Behavioral Neuroscience Branch, Intramural Research Program, NIDA-NIH, Baltimore, MD, USA.
Abstract:
In this issue of Neuron, Chen et al.1 found that lateral septum Esr1-expressing cells respond to both non-drug and drug rewards. Mice will lever press for optogenetic stimulation of these neurons, which are also critical to methamphetamine locomotor sensitization, conditioned place preference, self-administration, and reinstatement.
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