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Related Concept Videos

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  3. Research Domains
  5. Biomedical And Clinical Sciences
  7. Oncology And Carcinogenesis
  9. Predictive And Prognostic Markers
  11. Success Rate Of Fiducial Marker Placement For Treatment Of Esophageal Or Rectal Cancers: A Prospective Multicenter Study (fidecho Study) (with Video)

Success rate of fiducial marker placement for treatment of esophageal or rectal cancers: a prospective multicenter study (FIDECHO study) (with video)

Marine Camus1, David Karsenti2, Jonathan Levy3

  • 1Centre d'endoscopie digestive, Hôpital Saint Antoine, APHP, Paris, France; Sorbonne Université, Paris, France.

Gastrointestinal Endoscopy
|August 22, 2024

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View abstract on PubMed

Summary
This summary is machine-generated.

Endoscopic ultrasound-guided fiducial marker placement is safe and effective for esophageal and rectal cancers, demonstrating a high success rate and no adverse events. Markers remained visible throughout radiation therapy, ensuring treatment accuracy.

Area of Science:

  • Gastroenterology
  • Oncology

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  • Medical Imaging

    • Background:

    • Limited data exists on the feasibility and safety of endoscopic ultrasound (EUS)-guided fiducial marker placement for esophageal and rectal cancers.
    • Accurate tumor localization is crucial for effective radiation therapy planning.

    Purpose of the Study:

    • To assess the success rate and safety of EUS-guided fiducial marker placement in patients with esophageal or rectal cancer.
    • To evaluate the duration of fiducial marker visibility during radiation therapy.

    Main Methods:

    • A prospective multicenter study involving 33 patients with rectal or esophageal tumors.
    • Utilized EUS guidance with a 22-gauge fiducial needle for marker placement.
    • Primary endpoint: successful marker release at proximal and distal tumor ends; secondary endpoints: adverse events, procedure time, and marker retention.

    Main Results:

    • A high success rate of 93.9% for fiducial marker placement was achieved.
    • The average procedure time was 12.5 minutes, with no reported adverse events.
    • Fiducial markers remained visible on imaging in all patients post-radiation therapy.

    Conclusions:

    • EUS-guided fiducial marker placement is a safe and highly successful procedure for esophageal and rectal tumors.
    • The technique offers a short procedure time and excellent marker retention throughout radiation therapy.
    • This method enhances radiation therapy accuracy for gastrointestinal malignancies.