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Utilizing the Modified T-Maze to Assess Functional Memory Outcomes After Cardiac Arrest
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Long term functioning with poor neurologic outcome after cardiac arrest.

Sjoukje Nutma1, Ozzy Roesink2, Caroline M van Heugten3

  • 1Department of Clinical Neurophysiology, Technical Medical Center, University of Twente, Enschede, the Netherlands; Department of Neurology, Medisch Spectrum Twente, Enschede, the Netherlands.

Resuscitation
|August 22, 2024
PubMed
Summary

Recovery towards independence is limited for comatose cardiac arrest survivors with severe neurological disability. Most long-term survivors report satisfaction with their quality of life despite ongoing challenges.

Keywords:
Cardiac arrestPoor neurological outcome

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Area of Science:

  • Neurology
  • Cardiology
  • Rehabilitation Medicine

Background:

  • Comatose cardiac arrest survivors often experience severe neurological disability, with approximately 6% having a Cerebral Performance Categories (CPC) score of 3 at six months.
  • Limited data exists on the long-term recovery potential in cognitive, emotional, and quality of life domains for these patients.

Purpose of the Study:

  • To estimate the probability of recovery towards independence in patients with severe neurological disability (CPC3) at six months post-cardiac arrest.
  • To assess long-term outcomes in cognition, mood, and quality of life.

Main Methods:

  • Prospective registry of comatose cardiac arrest patients admitted between 2013-2017 in two Dutch hospitals.
  • Inclusion criteria: CPC score of 3 at six months post-cardiac arrest.
  • Follow-up until November 2023, assessing CPC score, cognition, mood, and quality of life using established questionnaires.

Main Results:

  • Of 667 patients, 29 (4.3%) had CPC3 at six months.
  • At a median of 8 years post-arrest, 12 of 13 surviving patients remained CPC3 (92%), with one improving to CPC2 (8%).
  • Only one survivor (14%) achieved independence in daily living; all survivors reported cognitive impairments, and most experienced physical limitations.

Conclusions:

  • The probability of achieving independence is low for patients with severe neurological disability at six months post-cardiac arrest.
  • Despite significant long-term disability, most survivors report satisfaction with their quality of life.
  • Cognitive rehabilitation is frequently missed, highlighting a potential area for intervention.