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Related Concept Videos

The Parathyroid Glands00:59

The Parathyroid Glands

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The two pairs of parathyroid glands embedded within the posterior surface of the thyroid gland are restricted by a dense capsule around them. These glands comprise two distinct cell populations—parathyroid oxyphil and parathyroid principal cells- pivotal in calcium homeostasis.
Oxyphil cells, whose functions remain elusive, emerge during late puberty, adding a layer of complexity to the parathyroid gland's intricacies. In contrast, principal parathyroid cells undertake a vital role by...
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Updated: Jun 15, 2025

Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging
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Same-day parathyroidectomy for primary hyperparathyroidism -an over 20-year practice.

Chandler A Annesi1, Andrea Gillis1, Jessica M Fazendin1

  • 1Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama, USA.

World Journal of Surgery
|August 22, 2024
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Same-day parathyroidectomy is safe and increasingly common. Older Black patients and those on anticoagulants are more likely to require inpatient surgery, despite similar complication rates.

Keywords:
outpatientparathyroidparathyroidectomy

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Area of Science:

  • Endocrinology
  • Surgical Oncology
  • Health Services Research

Background:

  • Same-day parathyroidectomy is gaining traction due to cost savings and comparable safety profiles.
  • Previous research indicates minimal differences in postoperative outcomes between same-day and inpatient procedures.

Purpose of the Study:

  • To investigate demographic, risk factor, and comorbidity associations with same-day versus inpatient parathyroidectomy.
  • To analyze trends in parathyroidectomy practice patterns over two decades.

Main Methods:

  • A prospective database of 2948 primary hyperparathyroidism surgeries from 2001-2022 was analyzed.
  • Patients were classified into same-day or inpatient cohorts.
  • Demographic, risk factor, and comorbidity data were examined, with trend analysis over time.

Main Results:

  • In 2013-2022, inpatient surgery patients were more likely to be Black and use anticoagulation/antiplatelet therapy.
  • Multivariable analysis confirmed older age and Black race increased odds of inpatient parathyroidectomy.
  • The proportion of same-day surgeries significantly increased from 2001-2003 to 2019-2022.

Conclusions:

  • Same-day parathyroidectomy is a safe and established practice for high-volume surgeons.
  • Demographic factors, particularly age and race, influence the likelihood of requiring inpatient parathyroidectomy.
  • While same-day surgery is prevalent, specific patient demographics necessitate consideration for inpatient care.