Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Bone Remodeling

Bone Remodeling

Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.

Bone Remodeling and Repair

Bone Remodeling and Repair

Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during bone...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Effect of Season on Patient-reported Outcomes and Discharge Disposition in Total Hip and Knee Arthroplasty.

The Journal of the American Academy of Orthopaedic Surgeons·2026

Same author

A Comparison of Radiographic Alignment Using Patient-Specific and Standard Instrumentation in Total Ankle Arthroplasty.

Foot & ankle orthopaedics·2026

Same author

Stagnant Physician Reimbursement as Hospital Reimbursement Increases for Inpatient Total Knee Arthroplasty in Commercial Payors.

The journal of knee surgery·2026

Same author

Metal Hypersensitivity in Total Knee Arthroplasty: Innovation Disproportionate to Clinical Necessity.

The journal of knee surgery·2026

Same author

Association of Testosterone Supplementation with the Risk of Infection following Primary Total Hip Arthroplasty.

Hip & pelvis·2025

Same author

National Trends in Use and Complications of Cemented, Cementless, Manual, and Robotic-Assisted Total Knee Arthroplasty: 2016-2022.

The journal of knee surgery·2025

Search research articles

Related Experiment Video

Updated: Jun 15, 2026

In Vitro Application of a Wireless Sensor in Flexion-Extension Gap Balance of Unicompartmental Knee Arthroplasty

In Vitro Application of a Wireless Sensor in Flexion-Extension Gap Balance of Unicompartmental Knee Arthroplasty

Published on: May 5, 2023

Robot-Assisted Patellofemoral Arthroplasty.

Gloria Coden¹, Lauren Schoeller¹, Eric L Smith¹

¹New England Baptist Hospital, Boston, Massachusetts.

JBJS Essential Surgical Techniques

|August 23, 2024

Summary

Robotic-assisted patellofemoral arthroplasty offers pain relief for isolated knee arthritis when nonoperative treatments fail. This procedure aims to preserve natural knee movement and may improve patellar tracking.

More Related Videos

A Teleoperated Robotic System-Assisted Percutaneous Transiliac-Transsacral Screw Fixation Technique

A Teleoperated Robotic System-Assisted Percutaneous Transiliac-Transsacral Screw Fixation Technique

Published on: January 6, 2023

The Use of Mixed Reality in Custom-Made Revision Hip Arthroplasty: A First Case Report

The Use of Mixed Reality in Custom-Made Revision Hip Arthroplasty: A First Case Report

Published on: August 4, 2022

Related Experiment Videos

Last Updated: Jun 15, 2026

In Vitro Application of a Wireless Sensor in Flexion-Extension Gap Balance of Unicompartmental Knee Arthroplasty

In Vitro Application of a Wireless Sensor in Flexion-Extension Gap Balance of Unicompartmental Knee Arthroplasty

Published on: May 5, 2023

A Teleoperated Robotic System-Assisted Percutaneous Transiliac-Transsacral Screw Fixation Technique

A Teleoperated Robotic System-Assisted Percutaneous Transiliac-Transsacral Screw Fixation Technique

Published on: January 6, 2023

The Use of Mixed Reality in Custom-Made Revision Hip Arthroplasty: A First Case Report

The Use of Mixed Reality in Custom-Made Revision Hip Arthroplasty: A First Case Report

Published on: August 4, 2022

Area of Science:

Orthopedic Surgery
Biomedical Engineering

Background:

Patellofemoral arthroplasty is indicated for isolated patellofemoral arthritis unresponsive to conservative management.
The procedure aims to alleviate pain while preserving native knee kinematics.

Purpose of the Study:

To describe the technique and outcomes of robotic-assisted patellofemoral arthroplasty.
To highlight the importance of accurate preoperative planning and intraoperative execution.

Main Methods:

Preoperative imaging (radiographs, MRI, CT) to confirm diagnosis and plan surgery.
Utilizing the MAKO Surgical Robot for precise bone resection and implant placement.
Surgical steps include arthrotomy, inspection, patellar resurfacing, trochlear resection, and implant impaction.

Main Results:

Robotic-assisted patellofemoral arthroplasty can lead to improved pain and function in selected patients.
Potential for enhanced patellar tracking compared to non-robotic methods.
Accurate and efficient trochlear resurfacing is achievable with robotic assistance.

Conclusions:

Robotic-assisted patellofemoral arthroplasty is a viable option for isolated patellofemoral arthritis.
Careful patient selection and surgical technique are crucial for optimal outcomes.
The procedure may offer advantages in preserving tibiofemoral bone stock compared to total knee arthroplasty.