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Updated: Jun 29, 2026
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Robot-Assisted Kidney Transplantation
Published on: July 19, 2021
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Radical Prostatectomy in Kidney Transplant Recipients-A Multicenter Experience.
Jacob Schmidt1, Abdulbaki Yakac2, Robert Peters1
1Department of Urology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
European Urology Open Science
|August 23, 2024
Summary
Radical prostatectomy is a safe and feasible treatment for localized prostate cancer in kidney transplant recipients, showing acceptable oncologic outcomes. Careful screening is needed to avoid understaging in this population.
Area of Science:
- Urology
- Transplant Surgery
- Oncology
Background:
- Kidney transplant recipients (KTRs) face a higher risk of genitourinary cancers, including prostate cancer (PCa).
- An aging KTR population is projected to increase PCa prevalence.
- Understanding surgical outcomes for PCa in KTRs is crucial.
Purpose of the Study:
- To evaluate the safety and oncologic outcomes of radical prostatectomy (RP) in kidney transplant recipients.
- To compare perioperative and long-term outcomes of open RP versus robot-assisted RP (RARP) in KTRs.
Main Methods:
- Retrospective analysis of 62 KTRs undergoing RP between 2006-2023 across nine centers.
- Complications assessed using Clavien-Dindo classification.
- Kaplan-Meier method used for survival analyses (OS, BRFS, graft survival).
Main Results:
- No graft loss occurred post-RP.
- 50% of patients had no postoperative complications; 14.5% had grade ≥3 complications.
- Median overall survival was 128 months; median biochemical recurrence-free survival was 106 months.
Conclusions:
- RP is a viable and safe treatment for localized PCa in KTRs.
- Acceptable oncologic outcomes were observed.
- Enhanced screening for understaging is recommended for KTRs with PCa.
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