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Engineering NK cells with LNP-enabled IL-2 mRNA transfection: Steps toward affordable precision immuno-therapeutics

Gokulnath Mahalingam1, Nikunj Tandel2, Rajeev K Tyagi3

  • 1Centre for Stem Cell Research (CSCR) (a unit of inStem, Bengaluru), CMC Campus, Bagayam, Vellore 632002, TN, India.

Molecular Therapy. Nucleic Acids
|August 23, 2024
PubMed
Abstract

No abstract available in PubMed .

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Cytotoxic T cells are a vital component of the immune system. They have the remarkable ability to identify and target antigens on infected or abnormal cells. These antigens often originate from intracellular pathogens such as viruses or abnormal proteins cancer cells produce.
Immunological surveillance is the ability of immune cells to monitor and eliminate infected cells with intracellular pathogens, neoplastically transformed cells, and cells with non-self antigens. Cytotoxic T cells and NK...
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