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Budesonide Orodispersible Tablet for the Treatment of Refractory Esophageal Lichen Planus
Thomas Skinner1,2, Sharron Liang2,3, Santosh Sanagapalli1,2
1Division of Gastroenterology and Hepatology, St Vincent's Hospital, Sydney, Australia.
Abstract:
Esophageal lichen planus is an uncommon but highly morbid condition where effective treatments are limited. Diagnosis may be challenging and requires a high degree of clinical suspicion considering endoscopic, histopathological, esophageal, and extraesophageal manifestations. We describe a severe case of esophageal lichen planus and recurrent esophageal stricture that was refractory to acid suppression, local and systemic steroid formulations, and dilatation. We present the first reported use of budesonide orodispersible tablet for this condition, including the excellent clinical, endoscopic, and histopathological response.
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