Related Experiment Video
Updated: Jun 15, 2025

Self-assembly of Complex Two-dimensional Shapes from Single-stranded DNA Tiles
Published on: May 8, 2015
Emergence of Self-Replicating Hierarchical Structures in a Binary Cellular Automaton
1Adjacent Lab. bo@adjacentlab.com.
Abstract:
We have discovered a novel transition rule for binary cellular automata (CAs) that yields self-replicating structures across two spatial and temporal scales from sparse random initial conditions. Lower-level, shape-shifting clusters frequently follow a transient attractor trajectory, generating new clusters, some of which periodically self-duplicate. When the initial distribution of live cells is sufficiently sparse, these clusters coalesce into larger formations that also self-replicate. These formations may further form the boundaries of an expanding complex on an even larger scale. This rule, dubbed "Outlier," is rotationally symmetric and applies to 2-D Moore neighborhoods. It was evolved through genetic programming during an extensive search for rules that foster open-ended evolution in CAs. While self-replicating structures, both crafted and emergent, have been created in CAs with state sets intentionally designed for this purpose, the Outlier may be the first known rule to facilitate nontrivial emergent self-replication across two spatial scales in binary CAs.
Related Concept Videos
Binary Fission
Replication in Eukaryotes
Many Proteins Orchestrate Replication at the Origin
Eukaryotic replication follows many of the same...
Chromosome Structure
The centromere is a DNA sequence that links sister chromatids. This is also where kinetochores, protein complexes to which spindle microtubules attach, are constructed after the chromosome is replicated. The kinetochores allow the spindle microtubules to move the chromosomes within the cell during cell division.
Telomeres consist of non-coding repetitive nucleotide...
Distribution of Cytoplasmic Content
Distribution of cytoplasmic determinants
The cytoplasm contains various organelles, as well as salts, proteins, and water. The distribution of...
Replicative Cell Senescence
Viral Recombination

